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Article Abstract
The aim of the present study was to characterize the probiotic potential of 4 N-6 strain isolated from cow's milk. For this purpose, acid, bile salt, pancreatin, pepsin, phenol, and lysozyme tolerance, co-aggregation and auto-aggregation properties, phytase production, antibiotic resistance, and antibacterial properties were analyzed in vitro. The strain had relatively poor acid, bile salt, and pepsin tolerance. However, the strain showed a high pancreatin, lysozyme, and phenol tolerance. In addition, it exhibited moderate co-aggregation with and good autoaggregation. Furthermore, the cell-free supernatant of . 4 N-6 showed a high antimicrobial activity against (N32), (RK-485), and (RK-487). 4 N-6 was resistant to vancomycin, teicoplanin, gentamicin, and ceflazidime. The 4 N-6 strain did not show hemolytic activity. In addition, this strain was found to be able to produce phytase. All the findings obtained indicate that . 4 N-6 is promising as a potential probiotic candidate and has superior properties that can be evaluated as a probiotic in the future. However, further research and in vivo studies are needed to fully understand its mechanism of action and optimize its use as a probiotic.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12021581 | PMC |
| http://dx.doi.org/10.1002/fsn3.70205 | DOI Listing |
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