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The noticeable growth of road transport means that the protection of road infrastructure is becoming a critical issue. The main factor leading to the excessive degradation of roads are overloaded vehicles. The effective elimination of such vehicles from road traffic is possible through widespread usage of Weigh-In-Motion (WIM) systems for direct mass enforcement, thus eliminating the need for "manual" vehicle checks which are currently carried out by the appropriate services. WIM mass enforcement systems require strict metrological control, meaning that an initial verification, conducted at the moment when the system is installed, and subsequent periodic verifications are required. These operations aim to ensure that vehicle weighing error is consistently maintained within a permissible range of values. Fulfilment of this condition allows for the minimisation of the probability that a vehicle loaded within normative limits will be classified as overloaded. The long-term study of two WIM systems located on provincial road 975 in Wielka Wies, in southern Poland, equipped with load sensors made using different technologies (strain gauge sensors and quartz sensors) and in different weather conditions, has allowed us to formulate recommendations regarding the frequency with which subsequent verifications should be performed in order to ensure the reliability of the weighing results. This paper presents the results of these studies and conclusions formulated based on them; in this case, they showed a verification of the system can be performed every 8 months. The conclusions and recommendations that we have presented concern primarily those WIM stations which were the object of our study and caution should be exercised when generalising these to other cases. Its novelty results from several premises. For the first time, long-term studies of two WIM systems equipped with load sensors made with different technologies were carried out. Both systems were installed on the same surface, in the immediate vicinity of each other. They were installed on a standard road and were subjected to the constant impact of road traffic with identical parameters. Tests of both WIM systems were performed periodically, using the pre-weighed vehicles method, in different seasons, for a period of 15 months. During the tests, the same test vehicles drove through both WIM systems at the same speed. All of this resulted in the obtainment of a unique set of measurement data, the analysis of which allowed for the assessment and comparison of the proprieties of the load sensors made with both technologies.
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http://dx.doi.org/10.3390/s25082421 | DOI Listing |
Vaccines (Basel)
August 2025
myNEO Therapeutics, 9000 Ghent, Belgium.
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View Article and Find Full Text PDFEur J Pharm Sci
August 2025
Laboratory of Experimental Surgery (SURGX), Department of Human Structure and Repair, Ghent University, Ghent, 9000, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium. Electronic address:
Peritoneal metastases (PM) remain a significant clinical challenge due to their resistance to systemic chemotherapy. Intraperitoneal aerosolized drug delivery (IPADD) has shown promise as a localized treatment option; however, its efficacy is often limited by inadequate aerosol droplet distribution and poor tissue penetration. In this study, we enhance IPADD using electrostatic precipitation (eIPADD) and evaluate its performance through computational simulations and in vitro/ex vivo experiments.
View Article and Find Full Text PDFClin Epigenetics
August 2025
Cell Death Signaling-Epigenetics Lab, Department Biomedical Sciences, University of Antwerp, 2610, Wilrijk, Belgium.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide, but its pathophysiological mechanisms remain elusive. It is a progressive disease, encompassing hepatic steatosis, steatohepatitis with (out) fibrosis, and ultimately cirrhosis and hepatocellular carcinoma. DNA methylation (DNAm) is dysregulated in MASLD and may play a central role in its pathogenesis.
View Article and Find Full Text PDFData Brief
August 2025
CONSTRUCT- GEQUALTEC, University of Porto, Faculty of Engineering, 4200-465 Porto, Portugal.
Metallic railway bridges built during the 20th century are ageing, but their continued operation is essential for enhancing the capacity of the network. Structural degradation phenomena are a cause for concern, particularly fatigue, which requires accurate knowledge of service railway loads for structural integrity assessment in order to avoid unnecessary strengthening or premature bridge replacement. Quantifying present traffic scenarios is, therefore, critical and provides a basis for deriving past and future scenarios, given the challenges of implementing permanent weighing systems.
View Article and Find Full Text PDFPorcine Health Manag
July 2025
Department Discovery & Technology, MSD Animal Health, Wim de Körverstraat 35, Boxmeer, 5830 AA, The Netherlands.
Background: Enteric virus infections around time of weaning have always been related to pig diseases such as postweaning diarrhea. Little, however, is known about the virus infection pattern (species, timing and viral load) in clinically healthy pigs. Virus infections may help to train and shape the immune system and presumably only lead to clinical disease when uncontrolled.
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