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This study systematically reviewed the effectiveness of cognitive, affective, and combined approaches in doping prevention, considering the impact of athletes' active versus passive participation. Following the PRISMA 2020 guidelines and the PICOS framework, a literature search identified ten studies involving 3581 athletes (1094 women, 2487 men). Ten studies were included as a sample in the meta-analysis and meta-regression, which were used in the effect size calculation. This meta-analysis shows that anti-doping education programs effectively improve short-term doping intentions (ES = 0.29, < 0.001) and anti-doping behaviors (ES = -0.27, < 0.001), although there is a decline in the long-term effects (ES = -0.13, = 0.009). Moral behaviors were unaffected (ES = 0.01, < 0.001), suggesting that changing deeper values requires alternative approaches like mentorship. Passive participation negatively impacted doping intentions (ES = -0.40, = 0.004) and behaviors (ES = -0.40, = 0.022), highlighting the need for active engagement. Pre-experimental designs showed a negative effect on behaviors (ES = -0.74, = 0.023), emphasizing the importance of rigorous methodologies. While anti-doping education programs effectively influence short-term attitudes and intentions, sustaining behavioral change requires continuous reinforcement and active engagement. The decline in the long-term effects suggests that standalone interventions are insufficient to instill lasting anti-doping behaviors in athletes.
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http://dx.doi.org/10.3390/sports13040108 | DOI Listing |
ACS Appl Mater Interfaces
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School of Chemistry & Materials Engineering, Fuyang Normal University, Fuyang 236037, China.
Halide perovskite quantum dots (QDs) have demonstrated outstanding performance in light-emitting applications. However, the performance of blue perovskite QDs lags far behind that of their red and green counterparts, especially those with color coordinates approaching (0.131, 0.
View Article and Find Full Text PDFEnviron Res
September 2025
Jiangxi Provincial Key Laboratory of High-Performance Steel and Iron Alloy Materials,Jiangxi University of Science and Technology, Ganzhou 34100, China; School of Metallurgy Engineering, Jiangxi University of Science and Technology, Ganzhou 34100, China. Electronic address:
The thermal runaway of lithium-ion batteries (LIBs) releases a mixture of toxic and explosive gases, posing severe safety risks. High-performance sensors are critical for the early detection of these thermal runaway gases (TRGs) to prevent accident escalation. Herein, we systematically investigate Fe-X (X=C, P, S) atomic pair-modified g-CN (FCN, FPN, FSN) monolayers as potential sensing materials for six TRGs (CO, CO, H, CH, CH, and CH) using first-principles calculations.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
August 2025
School of Stomatology, Qingdao University, Qingdao 266023, PR China; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao 266003, PR China.
White spot lesions (WSLs) are the most common complication of orthodontic treatment, compromising dental health and significantly affecting aesthetics. To address this clinical challenge, this study aims to develop a dual-functional therapeutic strategy that simultaneously promotes the remineralization of demineralized enamel and inhibits the activity of cariogenic bacteria, thereby achieving effective prevention and treatment of WSLs. A hollow double-shell structured CuO@N/C nanozyme (H-CuO@N/C) was synthesized using a one-step hydrothermal method.
View Article and Find Full Text PDFSci Adv
September 2025
Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP3), National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, Department of Environmental Science & Engineering, Fudan University, Shanghai 200443, China.
Fentanyl and its analogs are a global concern, making their accurate identification essential for public health. Here, we introduce Fentanyl-Hunter, a screening platform that uses a machine learning classifier and multilayer molecular network to select and annotate fentanyl compounds using mass spectrometry (MS). Our classification model, based on 772 fentanyl spectra and spectral binning feature engineering, achieved an score of 0.
View Article and Find Full Text PDFArch Toxicol
September 2025
Faculty of Chemical and Food Technology, Slovak University of Technology, 812 37, Bratislava, Slovakia.
Cellular systems responsible for the formation and removal of reactive oxygen species (ROS), functioning within physiological limits, are essential for maintaining intracellular redox balance. This state is known as oxidative eustress. Key redox signaling molecules, such as superoxide anion radical (O) and hydrogen peroxide (HO), operate at nanomolar concentrations and are produced by NADPH oxidases (regulated by various factors), the mitochondrial electron transport chain (ETC), and numerous enzymes.
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