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Purpose: To investigate whether super-resolution deep learning reconstruction (SR-DLR) of MR myelography-aided evaluations of lumbar spinal stenosis.
Material And Methods: In this retrospective study, lumbar MR myelography of 40 patients (16 males and 24 females; mean age, 59.4 ± 31.8 years) were analyzed. Using the MR imaging data, MR myelography was separately reconstructed via SR-DLR, deep learning reconstruction (DLR), and conventional zero-filling interpolation (ZIP). Three radiologists, blinded to patient background data and MR reconstruction information, independently evaluated the image sets in terms of the following items: the numbers of levels affected by lumbar spinal stenosis; and cauda equina depiction, sharpness, noise, artifacts, and overall image quality.
Results: The median interobserver agreement in terms of the numbers of lumbar spinal stenosis levels were 0.819, 0.735, and 0.729 for SR-DLR, DLR, and ZIP images, respectively. The imaging quality of the cauda equina, and image sharpness, noise, and overall quality on SR-DLR images were significantly better than those on DLR and ZIP images, as rated by all readers (p < 0.001, Wilcoxon signed-rank test). No significant differences were observed for artifacts on SR-DLR against DLR and ZIP.
Conclusions: SR-DLR improved the image quality of lumbar MR myelographs compared to DLR and ZIP, and was associated with better interobserver agreement during assessment of lumbar spinal stenosis status.
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http://dx.doi.org/10.1007/s11604-025-01787-5 | DOI Listing |
World Neurosurg
September 2025
Department of Spinal Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Electronic address:
Background: Spinal cord perfusion impairment is a critical secondary mechanism in acute spinal cord injury (SCI). Although lumbar cerebrospinal fluid (CSF) drainage is widely used in cardiothoracic surgery, its use in SCI remains limited. This study presents an evaluation of the safety and feasibility of lumbar CSF drainage with intrathecal pressure (ITP) and spinal cord perfusion pressure (SCPP) monitoring in acute SCI patients.
View Article and Find Full Text PDFNeurochirurgie
September 2025
Neurosurgery Department, Pasteur 2 Hospital, University Hospital of Nice, France.
Background: Posterior lumbar fusion (PLF) has become one of the most common spinal surgery procedures. Early symptomatic loosening of the pedicle screw could be a critical complication, leading to pseudarthrosis. However, revision strategies for pedicle screw loosening are still under debate.
View Article and Find Full Text PDFProc Inst Mech Eng H
September 2025
IDMEC, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
Low back pain is estimated to affect more than 70% of the population. Recently, interspinous posterior devices are gaining attention as a less invasive alternative to the traditional pedicle screw systems. However, since most of these devices are not suitable for the L5-S1 segment, the goals for this study are to design a tailored fixation system for the L5-S1 level and to study its effects on the degenerated spine.
View Article and Find Full Text PDFProg Neurobiol
September 2025
Age-Related and Brain Diseases Research Center, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; Biomedical Science Institute, Kyung Hee University, Seoul, Republi
Lumbar spinal stenosis (LSS) is one of the most common spinal disorders in elderly people and is often accompanied by neuropathic pain. Although our previous studies have demonstrated that infiltrating macrophage contribute to chronic neuropathic pain in LSS rat model, the molecular mechanisms underlying macrophage activation and infiltration have not been fully elucidated. In this study, we examined the critical role of platelet-derived growth factor receptor (PDGFR) signaling pathway in neuropathic pain associated with macrophage infiltration and activation in LSS rats.
View Article and Find Full Text PDFWorld Neurosurg
September 2025
Department of Neurosurgery, The Spine and Spinal Cord Institute, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. Electronic address:
Background: Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) is widely adopted for the treatment of lumbar degenerative disease. Expandable cages are now increasingly used in MIS-TLIF to facilitate disc height restoration in narrow spaces. Despite theoretical advantages, the clinical and radiologic outcomes of expandable cage compared to static cage remain controversial.
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