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Article Abstract
Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous disorder with limited treatment options in pediatric patients. We report the case of a 9-year-old boy with juvenile PRP (type III), who achieved complete disease remission after treatment with secukinumab, an IL-17A inhibitor, following initial therapeutic resistance to topical agents. This case, notable for PRP onset after erythema infectiosum, highlights a potential infectious trigger and the therapeutic benefit of targeting the IL-17A pathway in PRP. Our findings support further exploration of secukinumab as a treatment option for juvenile PRP.
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