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Background: Breast reduction surgery has been recognized for its potential to improve quality of life in patients with macromastia or after unilateral oncological treatment. However, comparative analysis of different surgical techniques remains sparse. Patient-reported outcome measures have emerged as indispensable tools in assessing patient satisfaction and postoperative outcomes. Driven by the hypothesis of substantial differences between self-reported patient outcomes and professional assessments, this study aimed to compare different technical approaches, integrating both the patients' and plastic surgeons' perspectives.
Methods: A 10-year retrospective single-center cohort study was conducted to compare patient- and surgeon-reported outcomes using pre- and postoperative BREAST-Q questionnaires and aesthetic self-assessments. Outcomes and postoperative complication rates of different technical approaches were analyzed using photographic documentation.
Results: A total of 170 patients met the inclusion criteria, of which 92 agreed to further photographic documentation for aesthetic evaluation. The median follow-up duration was 4.9 years. BREAST-Q scores significantly improved across all surgical techniques, with comparable scores in both oncoplastic and nononcoplastic patients. Notably, patients reported greater satisfaction with the postoperative aesthetic outcomes than surgeons. Multivariable analysis confirmed body mass index as a significant risk factor for postoperative complications.
Conclusions: Breast reduction surgery improves both aesthetic outcomes and long-term quality of life, regardless of surgical technique or the use of oncoplastic methods. The discrepancy between patient and surgeon satisfaction highlights the need for a patient-centered approach, such as incorporating patient-reported outcome measures to evaluate postoperative results.
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http://dx.doi.org/10.1097/GOX.0000000000006709 | DOI Listing |
Front Surg
August 2025
Breast Unit, Cho Ray Hospital, Ho Chi Minh City, Vietnam.
Background: Breast cysts are more common in premenopausal women (61.5%), particularly between ages 35-50. Microwave ablation (MWA) has shown advantages in treating symptomatic cysts.
View Article and Find Full Text PDFFront Pharmacol
August 2025
Medical Insurance Office, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Background: The present study aimed to evaluate the cost-effectiveness of pembrolizumab combined with chemotherapy versus placebo plus chemotherapy for patients with previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer from the perspective of the Chinese healthcare system.
Methods: A Markov model was developed to track patients' transitions over 3-week cycles and evaluate the health and economic outcomes over a 10-year horizon for the two competing treatments. The survival data were gathered from the KEYNOTE-355 trial, and cost and utility values were obtained from the published studies.
NAR Genom Bioinform
September 2025
School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India.
The translatability of patient-derived xenograft (PDX)-generated clinical data into patient-specific outcomes for therapeutic guidance is limited by the challenges in generalizability of models across patients, treatments, and cancer types. Previously, machine learning (ML) models have been developed for the two most abundant cancer types, i.e.
View Article and Find Full Text PDFInt J Womens Health
August 2025
Doctoral Program, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia.
Background: Breast cancer remains the most prevalent malignancy among women worldwide and represents a significant global health burden. Advances in treatment have increased survivorship, but many patients continue to experience persistent physical and psychosocial challenges. Telehealth has emerged as a promising approach to delivering continuous, patient-centered care, particularly during the treatment and survivorship phases.
View Article and Find Full Text PDFRadiol Case Rep
November 2025
Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, 71122 Foggia, Italy.
We report a rare case of breast and axillary metastases in a 75-year-old man diagnosed with prostate carcinoma. Initially, the patient presented with lower urinary tract symptoms (LUTS) and elevated prostate-specific antigen (PSA) levels. Prostate cancer was confirmed by biopsy and treated with androgen deprivation therapy (ADT) and radiotherapy.
View Article and Find Full Text PDF