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Acute limb ischemia (ALI) can occur as a late complication in patients recovering from COVID-19. Although typically seen during the acute phase, ALI may present weeks to months later, making diagnosis more challenging. Symptoms, including acute limb pain, pallor, coldness, and absent pulses, can be misattributed to other post-viral issues. COVID-19 induces a prothrombotic state that persists after recovery, with increased D-dimer, fibrinogen, and endothelial dysfunction contributing to thrombus formation. Early diagnosis through clinical assessment and imaging is crucial to prevent irreversible limb damage. Treatment involves anticoagulation, revascularization, and supportive care, tailored to the patient's condition. Vigilance for late-onset ALI in post-COVID-19 patients is essential to improve outcomes and prevent limb loss.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006679 | PMC |
http://dx.doi.org/10.7759/cureus.80798 | DOI Listing |
Khirurgiia (Mosk)
September 2025
Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.
Objective: To analyze and improve postoperative outcomes in patients with acute lower limb ischemia (ALLI) and previous reconstructive infrainguinal interventions.
Material And Methods: The authors analyzed postoperative outcomes after 54 repeated interventions in patients with thrombosis of common femoral artery bifurcation, deep femoral artery and non-functioning femoropopliteal (tibial) prosthesis.
Results: External-iliac-deep femoral replacement were performed in 28 (52%) patients, extended deep femoral artery repair - in 16 (29.
Knee Surg Sports Traumatol Arthrosc
September 2025
Orthopaedic Research Foundation of Western Australia, Perth, Western Australia, Australia.
Purpose: The purpose of the study was to identify the safety and effectiveness of an accelerated (AR) versus conservative (CR) rehabilitation regimen following surgical repair of proximal hamstring tendon avulsions.
Methods: This prospective randomized controlled trial (RCT) allocated patients undergoing proximal hamstring tendon repair to either a braced, partial weight-bearing rehabilitation regime (CR = 30) or an accelerated, unbraced regime, which permitted full weight-bearing as tolerated (AR = 27). Patients were evaluated pre-operatively and at 6 weeks, 3 and 6 months post-surgery, via patient-reported outcome measures (PROMs), patient satisfaction and global rating of change (GRC) scores.
Trauma Surg Acute Care Open
September 2025
CRT 4, US Army Institute of Surgical Research Burn Center, Fort Sam Houston, Texas, USA.
Acute extremity compartment syndrome (CS) is a serious medical complication triggered by factors such as trauma, vascular injury, or prolonged compression, resulting in elevated intracompartmental pressure (ICP) and tissue ischemia. Diagnosis remains challenging, mainly relying on the subjective evaluation of clinical symptoms. Different animal models have been used to study pathophysiology and evaluate diagnostic and therapeutic approaches.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Infectious Diseases, Third People's Hospital of Chengdu, Chengdu, China.
Rationale: Japanese spotted fever (JSF) is a rare tick-borne disease caused by Rickettsia japonica. Atypical manifestations and a lack of standardized diagnostic assays often result in delayed diagnosis and treatment, potentially leading to life-threatening complications.
Patient Concerns: A 57-year-old immunocompetent female from a region with no previously reported JSF cases presented with acute-onset high-grade fever (39.
J Vasc Surg Cases Innov Tech
December 2025
Cooper University Hospital, Division of Vascular Surgery, Camden, NJ.
A 47-year-old patient was emergently placed onto venoarterial extracorporeal membrane oxygenation on postoperative day 1 after coronary artery bypass surgery for refractory ventricular tachycardic arrest. The patient subsequently lost pulses in the right lower extremity and was too unstable to be transported for a computed tomography scan or to the hybrid operating room for an angiogram. Bedside administration of contrast via the perfusion sheaths with concurrent portable radiograph allowed for imaging of the right lower extremity vasculature to assess for patency.
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