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Introduction: Endovascular thrombectomy has shown significant benefits for patients with large-vessel ischaemic stroke. However, many countries face challenges establishing effective thrombectomy delivery systems, even when thrombolysis services are already in place. Moreover, there is limited research on implementing thrombectomy care delivery, particularly for scale-ups in low- and middle-income countries. This study identifies the key drivers of enhancing thrombectomy delivery systems in three Canadian regions and provides lessons for health systems in transition.
Methods: A qualitative research design with a phenomenological approach was employed. From January to December 2022, at three comprehensive ischaemic stroke centres in Canada, we involved non-participant observation and in-depth interviews with 91 key informants, including care providers and administrators engaged in large-vessel stroke care. Guided by the Behaviour Change Wheel and Theoretical Domains Framework, the data were transcribed and analysed using thematic content analysis.
Results: Three critical themes emerged. First, establishing a cohesive, goal-oriented, multidisciplinary patient care team with an egalitarian culture is vital. Second, integrating specific feedback data is essential for continuous quality improvement and for optimising workflow through collective leadership. Lastly, even with existing thrombolytic services, centralised regional planning and outreach to local thrombectomy implementers is necessary. Development must occur at stroke centres and their associated peripheral hospitals to build effective thrombectomy care delivery systems.
Conclusions: Enhancing thrombectomy care delivery systems requires a stepwise approach: first, establishing multidisciplinary teams at the micro-level; next, fostering collective leadership for continuous quality improvement at the meso-level and finally, coordinating regional outreach and centralised planning at the macro-level. The Canadian experience highlights the importance of addressing these interconnected levels and underscores the critical role of central planning and collaboration between policymakers and care providers. These strategies offer a structured pathway for improving stroke care globally, particularly in transitioning health systems.
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http://dx.doi.org/10.1136/bmjoq-2024-003149 | DOI Listing |
Neurol Res
September 2025
Zeenat Qureshi Stroke Institute and Department of Neurology, University of Missouri, Columbia, MO, USA.
Background: The benefits of rehabilitation in acute ischemic stroke patients following thrombectomy remain underexplored. We assessed which activities of daily living (ADLs) show the greatest improvement after goal-directed therapy in an inpatient rehabilitation setting.
Methods: We retrospectively analyzed pre- and post-rehabilitation functional assessments in 40 acute ischemic stroke patients treated with mechanical thrombectomy.
Neurohospitalist
September 2025
Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Background And Purpose: Informed consent (IC) practices for endovascular thrombectomy (EVT) in acute stroke are not well elucidated. We investigated the roles and specialties of those obtaining EVT IC, aiming to provide insights for enhancing the process.
Methods: We conducted a survey from July- December 2023 among acute stroke care clinicians.
Medicine (Baltimore)
September 2025
Department of Nephrology and Blood Purification, Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
Rationale: This case report aims to highlight a rare but life-threatening complication of femoral venous catheterization and to describe a novel endovascular technique for its management. Non-tunneled femoral catheters provide rapid vascular access for emergency dialysis (e.g.
View Article and Find Full Text PDFIEEE Trans Med Robot Bionics
August 2025
Department of Mechanical and Aerospace Engineering, University of California San Diego, San Diego, CA 92093, USA.
Endovascular surgeries generally rely on push-based catheters and guidewires, which require significant training to master and can still result in high stress being exerted on the anatomy, especially in tortuous paths. Because these procedures are so technically challenging to perform, many patients have limited access to high-quality treatment. Although various robotic systems have been developed to enhance navigation capabilities, they can also apply high stresses due to sliding against the vascular walls, impeding movement and raising the risk of vascular damage.
View Article and Find Full Text PDFRes Pract Thromb Haemost
August 2025
Department of Pediatric Hematology, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, the Netherlands.
Background: Pulmonary embolism (PE) response teams are increasingly used in adult care to improve severe PE management. Understanding the epidemiology, treatment, and outcomes of severe PE in children is crucial to assessing the need for pediatric PE response teams in the Netherlands.
Objectives: To evaluate the incidence, management, and short-term outcomes of severe PE in Dutch pediatric patients.