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http://dx.doi.org/10.1007/s11604-025-01788-4 | DOI Listing |
PLoS One
September 2025
Department of Infection Control and Prevention, Graduate School of Medicine, Osaka University, Osaka, Japan.
Background: The SARS-CoV-2 pandemic has highlighted the critical deficiency of infectious disease (ID) specialists, a subspecialty that remains underrepresented among Japanese medical students.
Methods: This nationwide cross-sectional survey was administered between April and August 2024 via an online questionnaire distributed to medical students throughout Japan. The survey assessed awareness of and interest in ID specialization, categorizing students by academic year: lower (first- and second-year students), middle (third- and fourth-year students), and upper grades (fifth- and sixth-year students).
Eur J Pediatr
September 2025
Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, China.
Unlabelled: Enlarged vestibular aqueduct (EVA) is one of the most common inner ear malformations (IEMs) leading to hearing loss in children. Although its genetic and clinical characteristics have been studied, its manifestations in completely deaf children in China, especially those with or without incomplete partition type II (IP-II), are not yet fully understood. We conducted a comprehensive analysis of 123 pediatric EVA children with complete hearing loss.
View Article and Find Full Text PDFJ Inflamm Res
August 2025
Department of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, 515000, People's Republic of China.
Background And Aims: Inflammatory Bowel Disease presents significant management challenges, particularly in pediatric and elderly populations with refractory conditions. Despite advances in biologic therapies, current treatments remain limited with inconsistent response rates. This study investigated Upadacitinib efficacy in Asian adolescent and elderly populations with refractory IBD.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
August 2025
Hepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, Key Laboratory of Digital Intelligence Hepatology (Ministry of Education), School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China. Electronic address:
Background And Aims: This study evaluated the efficacy and safety of the thyroid hormone receptor β agonist HSK31679 in Asian patients with metabolic dysfunction-associated steatotic liver disease (MASLD).
Methods: This was a phase 2a, multicenter, randomized, double-blind, placebo-controlled study at 26 centers in China. Subjects with a liver fat content (LFC) of ≥ 8% at screening, when assessed by magnetic resonance imaging-proton density fat fraction, were eligible.
J Acoust Soc Am
August 2025
Department of Speech-Language-Hearing Sciences and Center for Neurobehavioral Development, University of Minnesota, Minneapolis, USA.
This study aimed to investigate open-set sentence recognition in quiet and amidst single-talker babble among Mandarin-speaking children with cochlear implants (CIs) to elucidate key contributing cognitive and linguistic factors influencing performance. Open-set sentence recognition was assessed in both conditions, alongside measurement of cognitive skills (operational efficiency and auditory short-term memory) and linguistic skills (oral vocabulary and syntactic competence) in kindergarten-aged children with CIs (n = 22; age = 59.8 ± 10.
View Article and Find Full Text PDF