Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Introduction: Studies on physical activity (PA) and dementia mainly focus on activity quantity or intensity. Yet PA requires neuro-coordination of movement, and it is unclear whether complexity of daily activity varies by cognitive status. Thus, we examined the association between PA complexity, using multiscale entropy, and cognitive function, mild cognitive impairment (MCI), and dementia in older adults in the Baltimore Longitudinal Study of Aging (BLSA).
Methods: A total of 637 older adults (age 73.9 ± 11.3 years) in the BLSA completed a 7-day wrist-worn accelerometer assessment and neuropsychological tests from 2015 to 2020. Using logistic regression and structural equation modeling, we examined cross-sectional associations of PA complexity with MCI/dementia and cognition. Cross-lagged panel models (CLPMs) were used to assess bidirectional associations at baseline and 2-year follow-up. Multivariable models were adjusted for age, sex, race, education years, body mass index, and comorbidities.
Results: Participants in the lowest tertile of PA complexity had over double the odds of MCI/dementia (odds ratio = 2.63, 95% confidence interval [CI]: 1.02 to 6.79, = 0.045) compared to those in the highest tertile in the fully adjusted model. Structural equation modeling showed that PA complexity was associated with global cognitive function (standardized B [SB] = 0.102, 95% CI: 0.033 to 0.171, = 0.004), executive function (SB = 0.119, 95% CI: 0.049 to 0.189, = 0.001), and visuospatial ability (SB = 0.096, 95% CI: 0.026 to 0.167, = 0.008). CLPMs showed bidirectional associations between lower PA complexity and poorer executive function.
Discussion: Lower complexity of accelerometry-detected movement is associated with poorer cognition and higher risk of MCI/dementia. Future studies should explore whether low PA complexity is an early indicator of dementia.
Highlights: Prior studies mainly focused on quantity or intensity of physical activity.Poorer cognitive function was associated with lower complexity of daily activity.Lower complexity of physical activity may be an early indicator of dementia.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982518 | PMC |
| http://dx.doi.org/10.1002/trc2.70077 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Airway obstruction and gender affect arterial stiffness in children with cystic fibrosis.
Turk J Pediatr
September 2025
Department of Cardiorespiratory Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye.
Background: Vascular changes are observed in children with cystic fibrosis (cwCF), and gender-specific differences may impact arterial stiffness. We aimed to compare arterial stiffness and clinical parameters based on gender in cwCF and to determine the factors affecting arterial stiffness in cwCF.
Methods: Fifty-eight cwCF were included.
Association of problematic internet use with health-related daily habits in adolescents: evidence from a school-based survey.
Turk J Pediatr
September 2025
Department of Pediatrics, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Türkiye.
Background: With the development of technology, easier access to the internet and its excessive use have led to problematic internet use (PIU). The prevalence of PIU and its association with lifestyle behaviors in adolescents have become subjects of increasing academic interest. This study aimed to determine the prevalence of PIU among Turkish high school students and to investigate its association with sleep, physical activity and dietary habits.
View Article and Find Full Text PDF[Reflections derived from report: The Lancet commission on medicine, nazism, and the holocaust: historical evidence, implications for today, teaching for tomorrow].
Cuad Bioet
September 2025
Universidad Católica de Murcia. Observatorio de Bioética de la Universidad Católica de Valencia. Carlos Albors, 34. 46220 Picassent
Although, in principle, the Lancet article Commission on Medicine, Nazism, and the Holocaust, aims to provide medical students with a moral compass to guide the future of medical practice as a social retaining wall against anti-Semitism, it deals with the Holocaust not from a philosophical point of view, but from a pedagogical one, resorting to didactic strategies from a historiographical approach. What seemed to be a plea against the behaviour of the Nazi doctors' experiments becomes a justification of the positive law of the liberal democracies in use. However, what it ignores is of the utmost importance: that the majority of the regime's doctors were tried and sentenced for their iniquitous actions, and yet, in contemporary Western society, an even greater danger is very much present: techno-science, which, as it stands, can once again compromise the identity, dignity and very life of the human person.
View Article and Find Full Text PDFPerceived reward certainty in the assessment of delay discounting.
J Exp Anal Behav
September 2025
Fralin Biomedical Research Institute at VTC, Roanoke, VA, United States of America.
Reward delays are often associated with reduced probability of reward, although standard assessments of delay discounting do not specify degree of reward certainty. Thus, the extent to which estimates of delay discounting are influenced by uncontrolled variance in perceived reward certainty remains unclear. Here we examine 370 participants who were randomly assigned to complete a delay discounting task when reward certainty was either unspecified (n=184) or specified as 100% (n = 186) in the task trials and task instructions.
View Article and Find Full Text PDFLong sequence temporal knowledge tracing for student performance prediction via integrating LSTM and informer.
PLoS One
September 2025
School of Electrical and Information Engineering, Hunan Institute of Technology, Hengyang, Hunan, China.
Knowledge tracing can reveal students' level of knowledge in relation to their learning performance. Recently, plenty of machine learning algorithms have been proposed to exploit to implement knowledge tracing and have achieved promising outcomes. However, most of the previous approaches were unable to cope with long sequence time-series prediction, which is more valuable than short sequence prediction that is extensively utilized in current knowledge-tracing studies.
View Article and Find Full Text PDF