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http://dx.doi.org/10.1016/j.jds.2025.01.023 | DOI Listing |
JAMA Netw Open
September 2025
Harvard Medical School, Boston, Massachusetts.
Importance: Research in behavioral economics has demonstrated that people have irrational biases, which make them susceptible to decisional shortcuts, or heuristics. The extent to which physicians consciously might use nudges to exploit these heuristics and thereby influence their patients' decision-making is unclear. In addition, ethical questions about the conscious use of nudges in medicine persist, yet little is known about how physicians experience and perceive their use.
View Article and Find Full Text PDFEur J Clin Microbiol Infect Dis
September 2025
School of Bioengineering and Biosciences, Department of Biochemistry, Lovely Professional University, Punjab, 144411, India.
Purpose: This study investigates codon usage and amino acid usage bias in the genus Acinetobacter to uncover the evolutionary forces shaping these patterns and their implications for pathogenicity and biotechnology.
Methods: Codon usage patterns were examined in representative genomes of the genus Acinetobacter using standard codon bias indices, including GC content, relative synonymous codon usage (RSCU), effective number of codons (ENC), and codon adaptation index (CAI). Neutrality and parity plots were employed to evaluate the relative influence of mutational pressure and natural selection on codon preferences.
Sleep Breath
September 2025
School of medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Introduction: It is well known that Obstructive Sleep Apnea (OSA) is a complex disease characterized by an Upper Airway (UA) collapse during sleep, with potential consequences on ENT districts. Recent evidence suggests a possible association with Eustachian Tube Dysfunction (ETD). However, the potential effects of both surgical and non-surgical therapeutic strategies on ET function remain poorly explored in the current literature.
View Article and Find Full Text PDFJ Youth Adolesc
September 2025
University of California, Davis, CA, USA.
School interethnic climate has interpersonal and intrapersonal implications for adolescent development, but little is known of how it influences their psychological adjustment over time, let alone what drives this influence. This study examined whether two components of identity-school belonging perceptions and ethnic-racial identity beliefs-mediate the association between 10th grade perceptions of school interethnic climate and 12th grade psychological adjustment. The analytic sample includes 849 students (50% girls; 30% Latinx, 27% White, 16% Asian/Pacific Islander, 18% Multiethnic, 6% African American/Black, 3% Other).
View Article and Find Full Text PDFMol Biol Rep
September 2025
School of Pharmacy, Heilongjiang University of Chinese Medicine, NO 24 Heping Road, 150040, Harbin, P. R. China.
Lysosome-dependent cell death (LDCD) is a regulated form of cell death initiated by increased lysosomal membrane permeability, leading to the cytoplasmic release of lysosomal enzymes and subsequent cellular damage. Molecular mechanisms controlling LDCD include lysosomal membrane instability and lysosomal enzyme release, which together lead to cell damage. A more profound comprehension of these underlying mechanisms may reveal new therapeutic targets for diseases associated with lysosomal dysfunction.
View Article and Find Full Text PDF