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The modern emphasis on food quality, nutritional value, and health benefits has increased demand for nutrient-rich foods. Incorporating functional foods with enhanced nutritional profiles into diets is becoming a key strategy in addressing chronic and acute diseases. In this study, a pot experiment was conducted on the 'Kashi Ratna' cultivar of Capsicum annuum L. under salinity levels of 50 and 100 mM as compared to control (0 mM). UHPLC-HRMS untargeted quantitative metabolomic profiling revealed a significant increase in bioactive compounds such as amino acids, vitamins, fatty acids, alkaloids, capsaicinoids, terpenoids and phenolics under salinity stress. While 50 mM led to higher accumulation of metabolites, but the overall impact of 100 mM salinity was higher, affecting more metabolites. Our findings highlight the potential for utilizing salinity-affected lands as a sustainable and cost-effective solution for enhancing nutritional quality of foods particularly in the context of Global Climate Change.
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http://dx.doi.org/10.1016/j.foodchem.2025.144255 | DOI Listing |
J Am Assoc Lab Anim Sci
March 2025
Animal Resources Center, Department of Surgery, University of Chicago, Chicago, Illinois; and.
The Guide for the Care and Use of Laboratory Animals provides recommendations on sanitation frequencies for rodent caging equipment; however, it allows for performance standards to be used when extending this frequency for individually ventilated cage (IVC) caging. Our institution wanted to reexamine our current standards of care for mouse IVC caging, which includes a 14-d cage bottom and bedding change as well as the use of corncob bedding. This was driven by desire to reduce the stress to mice associated with cage change, and by recent literature showing a potential improved absorbency and multiple health and welfare benefits of paper pulp cellulose bedding products.
View Article and Find Full Text PDFStroke
September 2025
Department of Neurology, Yale School of Medicine, New Haven, CT (L.H.S.).
Preclinical stroke research faces a critical translational gap, with animal studies failing to reliably predict clinical efficacy. To address this, the field is moving toward rigorous, multicenter preclinical randomized controlled trials (mpRCTs) that mimic phase 3 clinical trials in several key components. This collective statement, derived from experts involved in mpRCTs, outlines considerations for designing and executing such trials.
View Article and Find Full Text PDFJ Paediatr Child Health
September 2025
Federal University of Juiz de Fora, Juiz de Fora, Brazil.
Aim: To measure the prevalence of BF amongst Brazilian children aged 12-24 months, assess associated social determinants and evaluate the impact of maternal knowledge about its benefits.
Methods: A cross-sectional study was conducted between September and December 2024, using an online questionnaire completed by Brazilian mothers with children aged 12-24 months. Sociodemographic data were collected, including maternal and child age, education level, marital status, ethnicity, household income and employment status.
Expert Rev Med Devices
September 2025
Department of Physical Medicine and Rehabilitation, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Rae Bareli Road, Lucknow, Uttar Pradesh, INDIA 226014.
Introduction: The World Health Organization (WHO) reported in 2023 that approximately 1.3 billion people, or 16% of the global population, are living with a disability. Among these, locomotor disabilities constitute a significant portion, underscoring the urgent need for devices that enhance mobility and support daily living.
View Article and Find Full Text PDFJ Dent Educ
September 2025
College of Dentistry, Health Sciences Center, University of Oklahoma, Oklahoma City, Oklahoma, USA.
Purpose: Uganda faces significant oral health workforce shortages, limiting access to dental care. The Uganda Christian University School of Dentistry (UCUSoD) implemented a blended learning approach to enhance dental education by integrating online training. This qualitative study assesses the feasibility and effectiveness of hybrid learning in improving students' knowledge and preparedness for clinical practice.
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