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Background: Passive prosthetic knees incorporate extension assist mechanisms to enhance the swing phase of the gait cycle for persons with above/through-knee amputations. In conventional polycentric knees using a 4-bar linkage, the extension assist mechanism connects one of the bars to the body of the prosthesis. However, this design introduces a singularity in the spring action delivery, causing the spring to push the knee into flexion beyond a certain angle. In contrast, polycentric prosthetic knees with an extension assist mechanism that links the upper and lower parts of the knee eliminate the singularity feature, ensuring that the knee is pushed toward extension throughout the full range of motion.
Objective: This study aims to investigate the effects of different spring extension assist mechanisms in polycentric knees on the walking capacity of unilateral above/through-knee amputees.
Study Design: Repeated measures.
Methods: Gait data were collected at self-selected and fast speeds from 8 unilateral above/through-knee traumatic amputees using a 10-camera motion capture system. Participants trialed 2 different polycentric prosthetic knees with and without the singularity feature, both coupled with a solid-ankle-cushioned-heel prosthetic foot. They underwent gait analysis with both prosthetic knees, and a comparison analysis was conducted to examine the trial conditions.
Results: The symmetry between the prosthetic and intact knee flexion angles was higher for the design without singularity by 5.2% (p = 0.025) at self-selected speeds and by 7.7% (p = 0.003) at fast speeds. Also, peak prosthetic knee flexion angles were lower for the design without singularity by 9.4° (p < 0.001) at self-selected speeds and by 9.6° (p = 0.012) at fast speeds.
Conclusions: The extension assist mechanism without singularity improved the symmetry between the intact and prosthetic knee flexion angles by preventing excessive prosthetic knee flexion in the swing phase of the gait cycle.
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http://dx.doi.org/10.1097/PXR.0000000000000448 | DOI Listing |
Alzheimers Dement
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Department of Neurology, Beijing TianTan Hospital, Capital Medical University, Beijing, China.
Cognitive impairment and dementia, including Alzheimer's disease (AD), pose a global health crisis, necessitating non-invasive biomarkers for early detection. This review highlights the retina, an accessible extension of the central nervous system (CNS), as a window to cerebral pathology through structural, functional, and molecular alterations. By synthesizing interdisciplinary evidence, we identify retinal biomarkers as promising tools for early diagnosis and risk stratification.
View Article and Find Full Text PDFParasitol Res
September 2025
Laboratório de Parasitologia, Instituto Biomédico, Universidade Federal Fluminense (UFF), Bloco E, 5º Andar, 510-525,Outeiro São João Batista S/N, Niterói, Rio de Janeiro, 24020-141, Brazil.
Brazil is a major pig-producing country with production systems that include both industrial and family farms. In these facilities, parasitic diseases present an obstacle to production. This study aimed to estimate the prevalence and risk factors of the gastrointestinal parasites that infect pigs as well as to provide information for producers through extension activities.
View Article and Find Full Text PDFHand (N Y)
September 2025
Duke University, Durham, NC, USA.
Background: Dorsal wrist spanning plate (DWSP) fixation in distal radius fractures (DRFs) has been proposed to allow earlier mobilization in polytraumatized patients by enabling early weightbearing (WB) through the injured wrist. The purpose of this study is to compare radiographic and clinical outcomes in patients who bore weight through the injured wrist within the early postoperative period with patients who did not bear weight.
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J Robot Surg
September 2025
Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.
Dynamic joint balancing (DJB) in robotic-assisted total knee arthroplasty (RATKA) allows surgeons to simulate implant positioning and predict soft tissue balance intraoperatively before bone resection. Although virtual gap (VG) estimation is integral to this process, its accuracy in predicting the final gap (FG) after implantation remains uncertain. We conducted a retrospective analysis of 77 knees in 61 patients undergoing RATKA with the MAKO system.
View Article and Find Full Text PDFJ Contin Educ Health Prof
September 2025
Dr. Marcucci: Adjunct Faculty Member, Middle Tennessee State University, Physician Assistant Program, Murfreesboro, TN, and Adjunct Faculty Member, South College, Physician Assistant Program, Nashville, TN, and Adjunct Faculty Member, Lincoln Memorial University, Physician Assistant Program, Harroga
Introduction: Advanced practice providers (APPs), including physician assistants and nurse practitioners, benefit from structured onboarding curricula as they transition into specialty practice. These programs aim to enhance evidence-based knowledge, clinical skills, and core competencies, ultimately improving provider competency and health care quality. This scoping review seeks to map the existing literature on specialty-focused APP onboarding practices and identify knowledge gaps.
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