98%
921
2 minutes
20
Introduction: The early identification of brain tumors is essential for optimal treatment and patient prognosis. Advancements in MRI technology have markedly enhanced tumor detection yet necessitate accurate classification for appropriate therapeutic approaches. This underscores the necessity for sophisticated diagnostic instruments that are precise and comprehensible to healthcare practitioners.
Methods: Our research presents CNN-TumorNet, a convolutional neural network for categorizing MRI images into tumor and non-tumor categories. Although deep learning models exhibit great accuracy, their complexity frequently restricts clinical application due to inadequate interpretability. To address this, we employed the LIME technique, augmenting model transparency and offering explicit insights into its decision-making process.
Results: CNN-TumorNet attained a 99% accuracy rate in differentiating tumors from non-tumor MRI scans, underscoring its reliability and efficacy as a diagnostic instrument. Incorporating LIME guarantees that the model's judgments are comprehensible, enhancing its clinical adoption.
Discussion: Despite the efficacy of CNN-TumorNet, the overarching challenge of deep learning interpretability persists. These models may function as "black boxes," complicating doctors' ability to trust and accept them without comprehending their rationale. By integrating LIME, CNN-TumorNet achieves elevated accuracy alongside enhanced transparency, facilitating its application in clinical environments and improving patient care in neuro-oncology.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11979982 | PMC |
http://dx.doi.org/10.3389/fonc.2025.1554559 | DOI Listing |
Driven by eutrophication and global warming, the occurrence and frequency of harmful cyanobacteria blooms (CyanoHABs) are increasing worldwide, posing a serious threat to human health and biodiversity. Early warning enables precautional control measures of CyanoHABs within water bodies and in water works, and it becomes operational with high frequency in situ data (HFISD) of water quality and forecasting models by machine learning (ML). However, the acceptance of early warning systems by end-users relies significantly on the interpretability and generalizability of underlying models, and their operability.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Computer Science, COMSATS University Islamabad, Sahiwal, Pakistan.
The widespread dissemination of fake news presents a critical challenge to the integrity of digital information and erodes public trust. This urgent problem necessitates the development of sophisticated and reliable automated detection mechanisms. This study addresses this gap by proposing a robust fake news detection framework centred on a transformer-based architecture.
View Article and Find Full Text PDFPLoS One
September 2025
College of Business Administration, Northern Border University (NBU), Arar, Kingdom of Saudi Arabia.
The increasing dependence on cloud computing as a cornerstone of modern technological infrastructures has introduced significant challenges in resource management. Traditional load-balancing techniques often prove inadequate in addressing cloud environments' dynamic and complex nature, resulting in suboptimal resource utilization and heightened operational costs. This paper presents a novel smart load-balancing strategy incorporating advanced techniques to mitigate these limitations.
View Article and Find Full Text PDFBioinformatics
September 2025
Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.
Motivation: Representation learning has revolutionized sequence-based prediction of protein function and subcellular localization. Protein networks are an important source of information complementary to sequences, but the use of protein networks has proven to be challenging in the context of machine learning, especially in a cross-species setting.
Results: We leveraged the STRING database of protein networks and orthology relations for 1,322 eukaryotes to generate network-based cross-species protein embeddings.
IEEE Trans Biomed Eng
September 2025
Objective: Diffusion magnetic resonance imaging (dMRI) often suffers from low spatial and angular resolution due to inherent limitations in imaging hardware and system noise, adversely affecting the accurate estimation of microstructural parameters with fine anatomical details. Deep learning-based super-resolution techniques have shown promise in enhancing dMRI resolution without increasing acquisition time. However, most existing methods are confined to either spatial or angular super-resolution, disrupting the information exchange between the two domains and limiting their effectiveness in capturing detailed microstructural features.
View Article and Find Full Text PDF