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Article Abstract
Surface pre-reacted glass (S-PRG) fillers, a new type of bioactive molecule, can release various ions (Al, BO, Na, SiO, Sr, and F) and exhibit high biocompatibility, good antibacterial properties, low plaque accumulation, and enhanced osteoblast differentiation. An alkali-treated titanium layer with a porous nanonetwork structure (TNS) promotes cell adhesion and produces a stronger osseointegration effect than that of a non-treated titanium layer. In this study, the osseointegration effect of TNS was enhanced by incorporating an S-PRG eluate solution. The efficiencies of TNS coatings with different S-PRG concentrations were determined by performing surface analysis, cell experiments, and animal experiments. The results revealed that the introduction of the S-PRG eluate solution promoted the osteogenic ability of TNS. The combination of these two materials offers a novel approach to the investigation of oral implant materials.
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| http://dx.doi.org/10.4012/dmj.2024-236 | DOI Listing |
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