Article Synopsis
- The study finds that both natural populations and tumors adapt similarly to low oxygen (hypoxia), indicating a shared genetic response.
- Understanding how these adaptations work in natural settings could provide valuable insights into cancer biology.
- This knowledge may help uncover new targets for cancer treatments.
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Article Abstract
This study reveals a broad convergence in genetic adaptation to hypoxia between natural populations and tumors, suggesting that insights from natural populations could enhance our understanding of cancer biology and identify novel therapeutic targets. See related commentary by Lee, p. 875.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046333 | PMC |
| http://dx.doi.org/10.1158/2159-8290.CD-24-0943 | DOI Listing |
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