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To support patients with cancer in a palliative treatment phase with the integration of experiences of contingency into their life narrative, we developed a multi-modal approach: In Search of Stories (ISOS). ISOS consists of the following elements: filling out the self-report RE-LIFE questionnaire, drawing of Rich Pictures, and reading an exemplary story with a spiritual counselor, followed by a co-creation process with a professional artist. In the current article we illustrate how patients moved through the process of integration of experiences of contingency during the meetings of ISOS by presenting two case descriptions. All meetings of the first two patients who completed the ISOS project were audio recorded, imported into Atlas-Ti and analyzed by applying a phenomenological approach to deepen our understanding of the patient's experiences throughout the meetings. The two cases showed distinct differences on how the experience of contingency was dealt with and how the integration of experiences of contingency into the life narrative unfolded. Patients focused on life goals and values concerning connection with loved ones, and on leaving a legacy behind, which was expressed through creating a work of art. The current study provides preliminary insight into how patients can go through a process of integration of experiences of contingency into their life narrative, which could inform the development of future support for patients with advanced cancer dealing with experiences of contingency. Specifically, offering patients possibilities to express themselves through materials within an artistic setting could support these patients to find new words and additional non-linguistic ways of expressing their experiences, and thereby facilitate the integration of experiences of contingency into their life narrative.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11978074 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0319918 | PLOS |
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View Article and Find Full Text PDFPatient
September 2025
PPD Evidera Patient-Centered Research, Thermo Fisher Scientific, Waltham, MA, USA.
Background: Migraine care is often suboptimal owing to undertreatment, variation in clinical outcomes and administration methods among existing treatments, and between- and within-individual heterogeneity in the clinical course of migraine. In response to these challenges, preference studies have been increasingly conducted to inform treatment decision-making and development. However, gaps remain in understanding how treatment preferences have been assessed across different migraine studies.
View Article and Find Full Text PDFPsychol Res
September 2025
Berlin School of Mind and Brain & Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.
The existence of free will has been called into question by Benjamin Libet's seminal experiment, who argued that our conscious decision is preceded by an unconscious decision reflected in the readiness potential (RP). Alternatively, it has been argue that the RP rather reflects a decision process in which different signals accumulate until they reach the intention threshold, at which point an agent experience their intention simultaneously. This raises the question what type of signal is accumulated given that no external information is provided.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
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Behavioral Neuroscience Research Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD 21224.
Learning when to initiate or withhold actions is essential for survival, requiring the integration of past experiences with new information to adapt to changing environments. The prelimbic cortex (PL) plays a central role in this process, with a stable PL neuronal population (ensemble) recruited during operant reward learning to encode response execution. However, it is unknown how this established reward-learning ensemble adapts to changing reward contingencies, such as reward omission during extinction.
View Article and Find Full Text PDFPublic Opin Q
August 2025
Professor, Department of Political Science, Simon Fraser University, Burnaby, BC, Canada.
Understanding the realities of members of marginalized communities is central to the advancement of social and behavioral sciences. We argue that the development of data accurately representing the perspectives and experiences of such communities is fundamentally contingent on relationships of trust and accountability, and on researcher critical reflexivity. We showcase our methodology in three vignettes based on how we conduct research with communities that are "hard to reach" due to their societal marginalization.
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