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The aim of this study was to explore the clinical value and accuracy of lung ultrasound in evaluating extravascular lung water (EVLW) in septic shock patients. Twenty-four septic shock patients who required mechanical ventilation and pulse indicating continuous cardiac output (PiCCO) monitoring in the Department of Critical Care Medicine of our hospital were included. Basic laboratory and demographic data for these patients were recorded. PiCCO monitoring was employed to measure EVLW at 0, 2, 6, 12, 24, and 48 h. The lung ultrasound score (LUS) was obtained via bedside transthoracic lung ultrasound (TTE), and the correlation between these two variables was analysed. Of 24 patients, 22 had satisfactory Doppler lung ultrasound results, and a strong correlation was detected between the LUS and EVLW measurements at the 0, 2, 6, 12, 24, and 48 h time points (all P < 0.001; ICC (interclass correlation coefficients) = 0.92, 0.91, 0.92, 0.90, 0.88, 0.71, respectively; all P < 0.001). The Bland‒Altman analysis revealed that only 4 (3.03%) points exceeded the limits of agreement. These findings suggest that pulmonary ultrasound scores can be utilized as an auxiliary metric for identifying EVLW in septic shock patients, suggesting that this technique is well suited for clinical application.
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http://dx.doi.org/10.1038/s41598-025-96554-x | DOI Listing |
Radiology
September 2025
Department of Electrical, Electronic, and Information Engineering "Guglielmo Marconi", University of Bologna, Cesena, Italy.
Radiology
September 2025
Department of Magnetic Resonance Imaging, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background MRI-derived arrhythmogenic substrate, including late gadolinium enhancement (LGE) and extracellular volume fraction (ECV), is indicative of sudden cardiac death (SCD) risk in nonischemic dilated cardiomyopathy (DCM). The relative prognostic value of LGE and ECV remains unclear. Purpose To evaluate the performance of LGE and T1 mapping in predicting SCD in patients with DCM and to explore clinical implementation.
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September 2025
Department of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Plc, Box 1234, New York, NY 10029.
Background The prognostic value of baseline visual emphysema scoring at low-dose CT (LDCT) in lung cancer screening cohorts is unknown. Purpose To determine whether a single visual emphysema score at LDCT is predictive of 25-year mortality from all causes, chronic obstructive pulmonary disease (COPD), and cardiovascular disease (CVD). Materials and Methods In this prospective cohort study, asymptomatic adults aged 40-85 years with a history of smoking underwent baseline LDCT screening for lung cancer between June 2000 and December 2008.
View Article and Find Full Text PDFBackground: Actinomyces graevenitzii is a relatively uncommon Actinomyces species, which is an oral species and predominantly recovered from respiratory locations [1,2]. It is a gram-positive anaerobic bacteria or microaerobic filamentation bacteria, which can induce pyogenic and granulomatous inflammation characterized by swelling and concomitant pus, sinus formation, and the formation of yellow sulfur granules. All tissues and organs can be infected; the most common type involves the neck and face (55%), followed by the abdominal and pelvic cavities (20%).
View Article and Find Full Text PDFAnal Chem
September 2025
Department of Radiotherapy, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215123, People's Republic of China.
Radiation therapy (RT) plays important roles in cancer treatment, and the efficacy of RT depends on the abscopal effect, which results in the regression of distant and untreated tumors through localized irradiation of a single tumor lesion. This effect is mediated by effector tumor antigen-specific T cells (ETASTs) activated by RT. Monitoring the radiation-induced changes in ETASTs can be used to predict the abscopal effect.
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