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Computed tomography pulmonary angiography (CTPA) is an essential diagnostic tool for identifying pulmonary embolism (PE). The integration of AI has significantly advanced CTPA-based PE detection, enhancing diagnostic accuracy and efficiency. This review investigates the growing role of AI in the diagnosis of pulmonary embolism using CTPA imaging. The review examines the capabilities of AI algorithms, particularly deep learning models, in analyzing CTPA images for PE detection. It assesses their sensitivity and specificity compared to human radiologists. AI systems, using large datasets and complex neural networks, demonstrate remarkable proficiency in identifying subtle signs of PE, aiding clinicians in timely and accurate diagnosis. In addition, AI-powered CTPA analysis shows promise in risk stratification, prognosis prediction, and treatment optimization for PE patients. Automated image interpretation and quantitative analysis facilitate rapid triage of suspected cases, enabling prompt intervention and reducing diagnostic delays. Despite these advancements, several limitations remain, including algorithm bias, interpretability issues, and the necessity for rigorous validation, which hinder widespread adoption in clinical practice. Furthermore, integrating AI into existing healthcare systems requires careful consideration of regulatory, ethical, and legal implications. In conclusion, AI-driven CTPA-based PE detection presents unprecedented opportunities to enhance diagnostic precision and efficiency. However, addressing the associated limitations is critical for safe and effective implementation in routine clinical practice. Successful utilization of AI in revolutionizing PE care necessitates close collaboration among researchers, medical professionals, and regulatory organizations.
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http://dx.doi.org/10.3389/fmed.2025.1514931 | DOI Listing |
Rev Esp Cardiol (Engl Ed)
September 2025
Servicio de Patología Forense, Instituto de Medicina Legal y Ciencias Forenses de Sevilla, Seville, Spain. Electronic address:
Introduction And Objectives: Pulmonary embolism (PE) may debut as sudden death (SD) in young and middle-aged adults. This study aims to determine the epidemiological and clinicopathological characteristics involved in SD due to PE in this age group and the underlying risk factors.
Methods: Multicenter retrospective noncontrolled study based on forensic autopsies performed in individuals aged 12 to 49 years at 3 forensic pathology services in Spain (Valencia, Biscay, and Seville) over an 8-year period (2010-2017).
J Orthop Sci
September 2025
Department of Health Administration and Policy, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-Ku, Sendai, Miyagi 980-8574, Japan. Electronic address:
Background: Obesity is associated with an increased risk of complications after total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA), particularly in Western populations. However, the effect of severe obesity (body mass index [BMI] ≥ 35 kg/m) on postoperative complications in Japanese patients remains unclear.
Methods: We conducted a retrospective cohort study using Japan's Diagnosis Procedure Combination (DPC) database, including patients who underwent TKA or UKA between April 2016 and March 2023.
Rev Esp Cardiol (Engl Ed)
September 2025
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, España; Servicio de Cardiología, Hospital Clínico de Santiago de Compostela, Santiago de Compostela, España.
Introduction And Objectives: This report presents the 2024 activity data from the Interventional Cardiology Association of the Spanish Society of Cardiology (ACI-SEC).
Methods: All interventional cardiology laboratories in Spain were invited to complete an online survey. Data analysis was conducted by an external company and then reviewed and presented by the ACI-SEC board.
J Thromb Thrombolysis
September 2025
Department of Haematology, Northern Hospital, 185 Cooper St, Epping, VIC, 3076, Australia.
Iliofemoral deep vein thrombosis (IFDVT) is associated with potential for poor outcomes despite optimal anticoagulation therapy. To characterize the real-world management of IFDVT in an Australian population. Retrospective evaluation of IFDVT cases managed at Northern Health, Australia from January 2011 to December 2020 was performed and compared to non-iliofemoral lower limb DVTs (non-IFDVT) (n = 1793).
View Article and Find Full Text PDFOpen Heart
September 2025
Division of Pulmonary Circulation, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan
Background: Balloon pulmonary angioplasty (BPA) improves haemodynamics in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Previous studies on BPA have set the treatment objective to achieve a mean pulmonary arterial pressure (mPAP) of <30 mm Hg. However, the clinical impact of mPAP after BPA remains unclear.
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