98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/00273171.2025.2443364 | DOI Listing |
J Int Neuropsychol Soc
September 2025
Center for Health Assessment Research and Translation, University of Delaware, Newark, DE, USA.
Objective: Because of the complexity of Alzheimer's Disease (AD) clinical presentations across bio-psycho-social domains of functioning, data-reduction approaches, such as latent profile analysis (LPA), can be useful for studying profiles rather than individual symptoms. Previous LPA research has resulted in more precise characterization and understanding of patients, better clarity regarding the probability and rate of disease progression, and an empirical approach to identifying those who might benefit most from early intervention. Whereas previous LPA research has revealed useful cognitive, neuropsychiatric, or functional subtypes of patients with AD, no study has identified patient profiles that span the domains of health and functioning and that also include motor and sensory functioning.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
July 2025
To leverage the abundant speech data available for pretraining, current models excel in generalization across diverse tasks. Nevertheless, real-world challenges emerge when addressing unfamiliar speech scenarios far from the pretrained speech, owing to the domain shift between pretraining (source) and fine-tuning (target) data. To overcome this barrier, we propose a variational Bayesian adapter (VB-Adapter) for cross-domain speech representation learning during fine-tuning.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
July 2025
Accurate identification and classification of white blood cells are essential for diagnosing hematological malignancies and analyzing blood disorders. Existing approaches predominantly leverage masked autoencoders (MAEs) to extract intrinsic blood cell features through image reconstruction as a pretext task. However, these methods encounter two critical challenges: (1) their generalization performance deteriorates under domain shifts caused by variations in staining techniques, illumination conditions, and microscope settings, and (2) the learned data distribution often deviates from the true distribution of blood cell features.
View Article and Find Full Text PDFBMC Cancer
July 2025
Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Objective: This study employed a biopsychosocial framework to develop structural equation models(SEM)quantifying the multidimensional impact of pain on quality of life in cancer patients, aiming to provide scientific evidence and novel clinical perspectives for evidence-based pain management strategies.
Methods: This cross-sectional study recruited participants experiencing chronic cancer-related pain using convenience sampling from a tertiary cancer hospital in Shandong Province, China, between January and February 2024. Data collection involved face-to-face administration of the Brief Pain Inventory-Short Form and the Quality of Life Questionnaire-Function 17.
J Adolesc Health
July 2025
Division of Neurology, Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, California.
Purpose: Financial adversity has been associated with altered subcortical neurodevelopment and obesity risk. However, no studies have examined these relationships in tandem. Food intake is influenced by the subcortex; thus, we examined whether financial adversity moderated bidirectional relationships between neurodevelopment and body mass index (BMI) in early adolescence.
View Article and Find Full Text PDF