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A 62-year-old otherwise healthy Caucasian female patient presented to the emergency department with a one-day history of severe abdominal pain, accompanied by nausea and non-bloody emesis. She did not report any prior similar episodes and denied any history of abdominal surgery. Although she did not report a history of diagnosed endometriosis, she did report a history of dysmenorrhea. Laboratory tests in the emergency room showed mild leukocytosis. A computed tomography (CT) scan of the abdomen showed a small bowel obstruction with a transition point in the right lower quadrant with associated reactive enteritis. A diagnostic laparoscopy was subsequently performed. Intraoperatively, we found an adhesive band from the appendix to the sigmoid colon resulting in an internal hernia. Laparoscopic adhesiolysis was performed to release the adhesive band, and since the appendix looked a little abnormal, the decision was made to perform an appendectomy. Her surgical pathology showed endometriosis near the appendiceal tip, estrogen receptor-positive (ER+). Her peritoneal fluid cytology was negative for malignant cells. The patient did well post-operatively and had no complications.
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http://dx.doi.org/10.7759/cureus.79717 | DOI Listing |
Int J Surg
September 2025
Department of Data Science, City University of Hong Kong, Hong Kong, SAR, China.
Background: Water hardness, which refers to the level of dissolved calcium and magnesium salts, is of significant public health concern due to its potential impact on health. The association between water hardness and digestive diseases remains underexplored, with limited evidence from small-scale clinical studies. Given the rising prevalence of digestive disorders worldwide, large-scale cohort studies are needed to address this gap in the literature.
View Article and Find Full Text PDFDan Med J
August 2025
Department of Hepatology and Gastroenterology, Aarhus University Hospital.
Introduction: A no-biopsy approach has been suggested for diagnosing coeliac disease (CD) in adult patients. This approach is already well established in diagnosing children with CD. This study aimed to evaluate the accuracy of IgA anti-tissue transglutaminase (IgA anti-tTG) in predicting duodenal mucosal lesions diagnostic of CD in adult patients.
View Article and Find Full Text PDFInt J Nanomedicine
September 2025
The First Hospital of Hunan University of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Ulcerative colitis (UC) is a chronic inflammatory bowel disease, the incidence of which continues to rise globally, and existing therapeutic options are limited by low drug bioavailability and systemic side effects. In this study, we systematically investigated the challenges of the special gastrointestinal environment of UC patients for oral drug delivery, such as extreme pH, degradation by digestive enzymes, metabolism of intestinal flora and obstruction of the intestinal mucosal barrier, and summarized the potential of plant-derived Exosome-like Nanovesicles (PELNs) as a novel delivery system. PELNs are produced by plant cells and mainly consist of proteins, RNA, lipids and plant active molecules.
View Article and Find Full Text PDFRadiol Case Rep
November 2025
Department of Radiology and Diagnostic Imaging, Fundación Cardioinfantil-Instituto de Cardiología, St. 163a #13B-60, Bogotá, Colombia.
Obturator hernia is a rare but clinically significant cause of intestinal obstruction, particularly in elderly, thin women due to their anatomical predisposition. We present the case of a 79-year-old female with a history of hypertension and hip arthroplasty who developed acute abdominal pain, vomiting, and absence of flatus and bowel movements. Imaging with contrast-enhanced computed tomography (CT) revealed a right obturator hernia containing a small bowel loop, causing intestinal obstruction without signs of ischemia.
View Article and Find Full Text PDFEnterocolitis is a common gastrointestinal manifestation of immune-related adverse events (irAEs); however, only a few studies have reported on irAE enteritis with localized active inflammation in the small intestine. Here, we report the case of a 74-year-old man who developed diarrhea, abdominal pain, and oral intake difficulty and was subsequently hospitalized after receiving atezolizumab for pulmonary adenocarcinoma. Computed tomography and enterocolonoscopy revealed active inflammation in the small intestine but not in the colon, leading to the final diagnosis of irAE enteritis.
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