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Background: Residential programs have been utilized for the treatment of adolescents with severe obesity, yet few have been evaluated.
Objective: The objectives were to (1) evaluate the effect of a long-term residential treatment program focused on treating adolescent girls with obesity and (2) explore girls' perceptions of weight management during and after participating in the program.
Methods: A mixed-methods approach was used to examine changes in weight outcomes over time among adolescent girls who completed the program ( = 12), and conduct qualitative interviews to explore perceptions of weight management after completion ( = 5).
Results: Girls in the program showed a reduction in mean BMI of 16.1 ± 4.2 kg/m (-36.3% ± 5.9%) over a mean of 57 weeks. At follow-up, three participants regained weight while two maintained their completion weight. The program shifted girls' health goals from weight loss to improved overall health. Experiences of social connection and disconnection were identified as components that impacted weight management trajectories over time.
Conclusion: This program demonstrated clinically meaningful improvements in BMI. The structured nature and the emphasis on therapeutic methods were key components of the program. Social support was identified by participants as being integral to successful weight maintenance over time.
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http://dx.doi.org/10.1002/osp4.70049 | DOI Listing |
Eur J Radiol
September 2025
Department of Radiology, Affiliated Hospital of Hebei University, Baoding 071000, China. Electronic address:
Purpose: The present study aimed to develop a noninvasive predictive framework that integrates clinical data, conventional radiomics, habitat imaging, and deep learning for the preoperative stratification of MGMT gene promoter methylation in glioma.
Materials And Methods: This retrospective study included 410 patients from the University of California, San Francisco, USA, and 102 patients from our hospital. Seven models were constructed using preoperative contrast-enhanced T1-weighted MRI with gadobenate dimeglumine as the contrast agent.
N Engl J Med
September 2025
Department of Health Promotion and Policy, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst.
Background: In 2019, seven county correctional facilities (jails) in Massachusetts initiated pilot programs to provide all Food and Drug Administration-approved medications for opioid use disorder (MOUD).
Methods: This observational study used linked state data to examine postrelease MOUD receipt, overdose, death, and reincarceration among persons with probable opioid use disorder (OUD) in carceral settings who did or did not receive MOUD from these programs from September 1, 2019, through December 31, 2020. Log-binomial and proportional-hazards models were adjusted for propensity-score weights and baseline covariates that remained imbalanced after propensity-score weighting.
Lupus
September 2025
Department of Pediatrics, All India Institute of Medical Sciences, Jodhpur, India.
A 16-year boy had a history of rash, oral ulcers, alopecia, photosensitivity, cheilitis, and weight loss, for which he was started on steroids, methotrexate, and hydroxychloroquine from outside. Three years later, he developed pericardial effusion and peripheral neuropathy, that were managed at an outside hospital. Later, he presented to us with weight loss, diffuse rash, left facial palsy, and left lateral rectus palsy.
View Article and Find Full Text PDFVet Res Commun
September 2025
Department of Physiology, Faculty of Veterinary Medicine, Cairo University, PO 11221, Giza, Egypt.
This comprehensive review examines the versatile applications and effects of Moringa oleifera across multiple fish species in aquaculture systems amid growing challenges of rising feed costs and antimicrobial resistance. M. oleifera, commonly called the Miracle tree, contains an exceptional nutritional profile with high protein content (22.
View Article and Find Full Text PDFCurr Atheroscler Rep
September 2025
Department of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.
Purpose Of Review: Despite major advances in the treatment and prevention of atherosclerotic cardiovascular disease (ASCVD), a substantial burden of residual risk remains Obesity has been redefined as a primary and independent drivers of cardiovascular morbidity and mortality warranting focused attention.
Recent Findings: Obesity is now recognized as a chronic disease and a central contributor to residual cardiovascular risk through mechanisms including systemic inflammation, insulin resistance, dyslipidemia, and endothelial dysfunction. This review addresses the limitations of conventional obesity management and highlights emerging pharmacological therapies targeting the underlying adiposopathy.