Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Introduction: Patients with schizophrenia spectrum disorders (SSD), particularly patients with schizophrenia, have social cognitive impairments characterized by difficulties in emotion recognition, the ability to attribute mental states, explaining the causes of events, and identifying and utilizing social cues. These impairments appear from early life and are associated with poor functional and social prognosis. The origin of these impairments is not fully understood. The inflammatory hypothesis is one of the pathophysiological hypotheses of schizophrenia. Inflammatory marker abnormalities are also present in the early stages of schizophrenia and are associated with neuronal degeneration. Following our main hypothesis, the aim of this work was to conduct a review to explore the relationship between social cognition and inflammatory markers in SSD.
Methods: The review included original studies reporting measures of social cognition and plasma levels of inflammatory markers in patients with SSD using the Pubmed, PsycINFO, and Embase databases. The PRISMA methodology was followed.
Results: Eleven studies were selected and analyzed. They showed significant correlations between plasma cytokine levels and theory of mind and facial emotion recognition abilities.
Conclusion: The correlations do not seem to be specific to social cognitive impairments, but our results support the hypothesis of a link between pro- and anti-inflammatory markers and cognition in SSD. In the future, other studies should be conducted to clarify this link from a diagnostic and therapeutic perspective: identification of inflammatory trait factors and patient subgroups and personalized anti-inflammatory therapies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955717 | PMC |
| http://dx.doi.org/10.1002/brb3.70384 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Adverse Childhood Experiences, Neurocognitive Functions, and Long-Term Mortality Risk.
JAMA Netw Open
September 2025
Social and Behavioral Sciences Branch, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
Importance: Higher intellectual abilities have been associated with lower mortality risk in several longitudinal cohort studies. However, these studies did not fully account for early life contextual factors or test whether the beneficial associations between higher neurocognitive functioning and mortality extend to children exposed to early adversity.
Objective: To explore how the associations of child neurocognition with mortality changed according to the patterns of adversity children experienced.
Predictors of change in sleep disturbance in Canadian long-term care facilities: a longitudinal analysis based on interRAI assessments.
Eur Geriatr Med
September 2025
School of Public Health Sciences, University of Waterloo, Waterloo, Canada.
Purpose: Sleep disturbance is prevalent in long-term care facilities (LTCFs), yet there is limited understanding of individual factors predicting changes in sleep within these populations. Our objective was to determine predictors of sleep disturbance in LTCFs and investigate variation in prevalence across facilities in two Canadian provinces-New Brunswick and Saskatchewan.
Method: This retrospective longitudinal cohort study used interRAI comprehensive health assessment data from 2016 to 2021, encompassing 21,394 older adults aged ≥ 65 years across 228 LTCFs.
Clinical Momentum: An Observational Study Identifying Latent Forces Driving Surgical Interventions for Older Adults Near the End of Life.
Ann Surg
September 2025
Department of Surgery, University of Wisconsin-Madison.
Objective: We evaluated the empirical fit of our model of clinical momentum for older adults with life-limiting illness undergoing unplanned surgery.
Background: Older adults often undergo surgery near the end of life, in contrast to generally stated preferences. Systems forces promoting intervention may produce nonbeneficial treatment despite advances in communication.
Instruments in Spanish to Assess the Mental Health of Adults With Intellectual Disabilities. A Systematic Review.
J Appl Res Intellect Disabil
September 2025
Department of Pedagogy, Faculty of Education and Social Work, University of Valladolid, Valladolid, Spain.
Background: Mental health (MH) problems are more common in people with intellectual disabilities (ID), yet under-diagnosis persists, which may be partly due to a lack of appropriate assessment tools. This study presents a systematic review of instruments used to assess MH problems in Spanish-speaking adults with ID.
Method: Following PRISMA guidelines, a search was conducted in Web of Science, PsycINFO, and Scopus using terms related to ID, MH and assessment.
Unveiling the dual-pathway effect of CSR perception environmental on employee pro-environmental behavior: evidence from Chinese marine enterprises.
Front Psychol
August 2025
Marine Disaster Reduction Center, Ministry of Natural Resources, Beijing, China.
To achieve the sustainable development goals and in response to the green development policies, many enterprises have actively incorporated corporate social responsibility (CSR) into their strategic plans in order to enhance environmental sustainability. This study explores the cognitive and emotional pathways through which perceived environmental CSR (PECSR) influences pro-environmental behavior (PEB) among employees in China's marine enterprises, based on the Cognitive-Affective Personality System theory. The research was conducted through data collection and verified through the structural equation model.
View Article and Find Full Text PDF