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Background: Even well-planned no-decompression dives can still produce inert gas bubbles that increase decompression sickness risk. A previously proposed formula for predicting post-dive bubble grades integrates individual factors (age, breathing gas consumption) with dive parameters (maximum depth, surface interval). This study aimed to confirm the formula's validity in an independent dataset and to find out whether detailed dive profile data are of further relevance in predicting echocardiography-derived post-dive bubble grades. Additionally, we explored whether machine learning models leveraging detailed dive profile data could enhance predictive accuracy.
Results: A total of 59 divers performed 359 no-decompression open-circuit air dives in freshwater and saltwater. Post-dive transthoracic echocardiography detected bubbles (Eftedal-Brubakk grade ≥ 1) in 29.8% of dives. Maximum depth, total dive time, air consumption, and age correlated significantly with observed bubble grades (r=0.37, r=0.16, r=0.27, r=0.13, respectively). The original prediction formula remained valid (r=0.39) and adequately captured higher-grade dives. Spending additional time in shallow water after deep segments reduced bubble formation. Machine learning approaches based on typical dive computer data (e.g. dive profile) provided stronger predictions (r=0.49).
Conclusions: This study shows that maximum depth, age, surface interval and total breathing gas consumption are sufficient predictors of post-dive bubble load in no-decompression air dives. This allows divers to individually adopt bubble-reducing measures-such as resting, hydrating, and extending surface intervals-once alerted to a higher-risk class. Integrating the formula into dive computers may offer real-time, individualised risk guidance and help prevent decompression sickness despite following computer-derived profiles in recreational diving.
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http://dx.doi.org/10.1186/s40798-025-00832-x | DOI Listing |
Eur J Pediatr
September 2025
Department of Pediatrics, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, 322000, China.
To evaluate the bubble-eliminating efficacy and safety of simethicone when used for gastrointestinal preparation before pediatric endoscopy. We conducted a comprehensive Literature search from inception to April 5, 2025, in PubMed, Embase, Web of Science, Cochrane library, Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Chinese VIP Information Database, and Wan Fang Med Database. For the quantitative analysis, mean difference (MD) was used to assess continuous outcomes and risk ratio for dichotomous outcomes.
View Article and Find Full Text PDFDig Dis Sci
August 2025
Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-Ku, Kyoto, 6028566, Japan.
Background: Gel immersion endoscopy is a novel method that uses gel to enhance the visual field. This study aimed to analyze the efficacy of magnified endoscopy under gel immersion for optimal visualization and characterization of colorectal tumors.
Methods: We retrospectively examined 107 lesions observed with blue-laser/light imaging (BLI) or narrow-band imaging (NBI) between June 2022 and July 2023 using the Japan NBI Expert Team classification.
Ultrasonics
December 2025
Division of Gastroenterology, University of Washington School of Medicine, Seattle, WA, United States of America; Center for Industrial and Medical Ultrasound, University of Washington, Seattle, WA, United States of America.
Boiling histotripsy (BH) is a promising method for mechanical tissue fractionation and liquefaction, utilizing millisecond-long high-intensity focused ultrasound (HIFU) pulses with shock fronts. Recent study has reported that cavitation bubbles induced during the BH pulse can move within the liquefied treated volume for a few milliseconds to seconds after each BH pulse ends. These bubble motions can be observed by ultrasound Doppler measurements, with maximum Doppler velocity showing significant potential as a metric to determine the treatment completion, as previously demonstrated in ex vivo setting.
View Article and Find Full Text PDFSmall
July 2025
The Beijing Key Laboratory of Multiphase Flow and Heat Transfer for Low Grade Energy Utilization, North China Electric Power University, Beijing, 102206, P. R. China.
To achieve robust and high-efficient thermal management at micro scale, this study focuses on interplay of a micro bubble blanket and lifting large bubbles on locally heated surfaces with nano-ridge structures. The micro bubble blanket covers the surface dynamically after heat fluxes exceed a criterion where heat transfer coefficients exhibit constant values, highlighting the robust and predictable two-phase heat transfer. By quantitative investigations of diameters as well as lifting speed of large bubbles, it ensures that convective boiling heat transfer mechanism dominates without forced convection, accounting for constant heat transfer coefficient at high-heat-flux regions.
View Article and Find Full Text PDFClin Ther
July 2025
Indonesian Molecule Institute, Malang, East Java 65151, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Brawijaya, Malang, East Java 65145, Indonesia.
Background: Chronic kidney disease (CKD) is a progressive condition with limited treatment options that often lead to significant morbidity. Oxyhydrogen nanobubbles (HHOnb), a form of ultrafine gas-in-liquid dispersion containing hydrogen and oxygen, have shown potential therapeutic benefits due to their antioxidative and anti-inflammatory properties. This exploratory case series investigates the effects of intravenous HHOnb therapy in three patients with varying stages of CKD.
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