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Purpose: This study aimed to evaluate the effectiveness of artificial intelligence (AI) in diagnosing focal nodular hyperplasia (FNH) of the liver using magnetic resonance imaging (MRI) and compare its performance with that of radiologists.
Methods: In the first phase of the study, the MRIs of 60 patients (30 patients with FNH and 30 patients with no lesions or lesions other than FNH) were processed using a segmentation program and introduced to an AI model. After the learning process, the MRIs of 42 different patients that the AI model had no experience with were introduced to the system. In addition, a radiology resident and a radiology specialist evaluated patients with the same MR sequences. The sensitivity and specificity values were obtained from all three reviews.
Results: The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the AI model were found to be 0.769, 0.966, 0.909, and 0.903, respectively. The sensitivity and specificity values were higher than those of the radiology resident and lower than those of the radiology specialist. The results of the specialist versus the AI model revealed a good agreement level, with a kappa (κ) value of 0.777.
Conclusion: For the diagnosis of FNH, the sensitivity, specificity, PPV, and NPV of the AI device were higher than those of the radiology resident and lower than those of the radiology specialist. With additional studies focused on different specific lesions of the liver, AI models are expected to be able to diagnose each liver lesion with high accuracy in the future.
Clinical Significance: AI is studied to provide assisted or automated interpretation of radiological images with an accurate and reproducible imaging diagnosis.
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http://dx.doi.org/10.4274/dir.2025.243095 | DOI Listing |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417915 | PMC |
Plant Dis
September 2025
Michigan State University, Department of Plant, Soil and Microbial Sciences, 105 CIPS, East Lansing, Michigan, United States, 48824;
Caliciopsis pinea is the ascomycete plant pathogen that causes caliciopsis canker disease on North American Pinus strobus (eastern white pine). Infections result in downgrading of lumber due to canker formation and overall loss of vigor in P. strobus, which is a critical cover species throughout its native range.
View Article and Find Full Text PDFInt J Lab Hematol
September 2025
Department of Hematology, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Background: T follicular helper (TFH) cell lymphoma is complex, and we hope to provide a new perspective for its diagnosis.
Methods: We analysed the immunophenotypes of 89 mature T-cell lymphomas, including 52 nodal lymphomas of TFH origin, as well as 32 benign lymph node samples and 30 healthy bone marrow samples, by flow cytometry (FCM).
Results: Among pan-T cell markers, CD4CD5CD3 is the typical pattern that distinguishes TFH lymphoma from other T-cell lymphomas.
J Imaging Inform Med
September 2025
Department of Biomedical Engineering, Gachon University, Seongnam-Si 13120, Gyeonggi-Do, Republic of Korea.
To develop and validate a deep-learning-based algorithm for automatic identification of anatomical landmarks and calculating femoral and tibial version angles (FTT angles) on lower-extremity CT scans. In this IRB-approved, retrospective study, lower-extremity CT scans from 270 adult patients (median age, 69 years; female to male ratio, 235:35) were analyzed. CT data were preprocessed using contrast-limited adaptive histogram equalization and RGB superposition to enhance tissue boundary distinction.
View Article and Find Full Text PDFRen Fail
December 2025
Department of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, China.
This study aimed to develop a predictive model and construct a graded nomogram to estimate the risk of severe acute kidney injury (AKI) in patients without preexisting kidney dysfunction undergoing liver transplantation (LT). Patients undergoing LT between January 2022 and June 2023 were prospectively screened. Severe AKI was defined as Kidney Disease: Improving Global Outcomes stage 3.
View Article and Find Full Text PDFJ Orthop Sci
September 2025
Department of Orthopaedic Surgery, NHO Saga Hospital, 1-20-1 Hinode, Saga 849-0923, Japan.
Background: Hounsfield units (HU) on computed tomography (CT) are strongly correlated with bone mineral density (BMD) and may aid in osteoporosis screening. However, there is no standardized method for assessing bone density in displaced femoral head fractures. This study aimed to measure HU values in the femoral head using preoperative post-fracture CT images of patients with intertrochanteric femoral fractures and investigate whether it correlated with BMD measured by dual-energy X-ray absorptiometry (DXA).
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