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Kidney disease is a dangerous disease that affects human health and causes various defects. Renal microbiological changes can be monitored using optical coherence tomography (OCT) images to identify the nature of the disease based on behavior during ischemia-reperfusion. Image analysis becomes the more sophisticated part of extracting information from feature dependencies from objects to identify the disease. Most methodologies use feature correlation dependencies in non-relation feature analysis-based disease identification with low precision and recall level. So, classification accuracy needs to be higher performance. To resolve this problem, we proposed the adaptive neuro-fuzzy inference system-based Resnet50 optimal convolutional neural network (ANFIS-CNN) method implemented using deep learning (DL) to monitor kidney disease. Initially, we analyze using OCT images collected from a standard repository. Furthermore, bidirectional filters can be used for preprocessing to reduce image noise. Gaussian filtering can be applied to identify the dependence of kidney structure. Afterward, the color density saturation can be analyzed through edge-based segmentation using the histogram equalization method, and the optimally extracted objects can be identified through edge-based segmentation. These spectral value-based relative feature detection thresholds are combined with texture point-based recursive spectral multiscale feature selection (RSMFS) to produce different entity contrasts. Then, spectral values are optimized with ANFIS-Resnet50 optimal CNN to classify the accuracy by selecting images. Moreover, the proposed method results in high classification accuracy up to 96.1 %, recall rate 95.18 % and precision up to 96.09 % well attained, enhancing their overall performance. The system develops high-performance image recognition for kidney disease monitoring.
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http://dx.doi.org/10.1007/s11255-025-04449-7 | DOI Listing |
J Proteome Res
September 2025
Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington 98195, United States.
Retinol binding protein 4 (RBP4), the circulating carrier of retinol, complexes with transthyretin (TTR) and is a potential biomarker of cardiometabolic disease. However, RBP4 quantitation relies on immunoassays and Western blots without retinol and TTR measurement. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simultaneous absolute quantitation of circulating RBP4 and TTR is critical to establishing their biomarker potential.
View Article and Find Full Text PDFVet Res Commun
September 2025
Department of Physiology, Faculty of Veterinary Medicine, Cairo University, PO 11221, Giza, Egypt.
This comprehensive review examines the versatile applications and effects of Moringa oleifera across multiple fish species in aquaculture systems amid growing challenges of rising feed costs and antimicrobial resistance. M. oleifera, commonly called the Miracle tree, contains an exceptional nutritional profile with high protein content (22.
View Article and Find Full Text PDFJ Nephrol
September 2025
Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, Health Psychology Section, King's College London, 5th Floor Bermondsey Wing, Guy's Campus, London Bridge, London, SE1 9RT, UK.
Background: Depression and anxiety are common in chronic kidney disease (CKD) and worsen clinical outcomes. Psycho-behavioural interventions offer a promising, non-pharmacological approach. However, most evidence comes from people with kidney failure with distinct treatment needs, limiting relevance to earlier stages of CKD, where timely support may enhance self-management and slow progression.
View Article and Find Full Text PDFMol Cell Biochem
September 2025
Peking University Third Hospital, Beijing, China.
Cardiovascular-Kidney-Metabolic (CKM) syndrome, a newly defined systemic disorder, is characterized by the pathological interplay among diabetes, chronic kidney disease (CKD), and cardiovascular disease (CVD). Recent studies have identified chronic inflammation not only as a central mediator in the pathological progression of CKM syndrome but also as a pivotal molecular hub that drives coordinated damage across multiple organ systems. Mechanistic investigations have revealed that aberrant activation of signaling pathways such as NF-κB, Wnt, PI3K-AKT, JAK-STAT, and PPAR constitutes a complex inflammatory regulatory network.
View Article and Find Full Text PDFInfection
September 2025
The Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Inge Lehmanns Vej 7, 16th floor, Copenhagen, 2100, Denmark.
Purpose: Infective endocarditis (IE) has been associated with severe outcomes when complicated by diabetes mellitus (DM). We aimed to report characteristics, microbial etiology, and mortality for patients with IE stratified by DM from a nationwide cohort.
Methods: We used Danish registries, and patients with first-time IE (2010-2020) were stratified by DM.