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Background: Guideline-directed medical therapy (GDMT) for patients with heart failure with reduced ejection fraction (HFrEF) is under-prescribed. Real-world data regarding contemporary GDMT prescribing and the impact of scalable interdisciplinary heart failure (HF) teams are needed.
Methods And Results: We retrospectively identified 2121 patients with HFrEF seen in 2022 in 4 community-based cardiology-practice sites that contained an embedded interdisciplinary HF team. After excluding 203 patients with missing data or encounters, GDMT prescribing was compared among those with (n = 1029) and without (n = 889) the support of the interdisciplinary HF teams. Patients were 33% female, 34% Black/African American, with an average age of 69 years. Patients seen by interdisciplinary HF teams achieved more comprehensive GDMT regimens compared to patients receiving routine care alone, as shown by higher 4-Pillar Intensification Scores (6.5 vs 4.7; P < 0.001). Using multivariable logistic regression models, patients whose care included an interdisciplinary HF team had higher odds (OR; 95% CI) of receiving sodium-glucose cotransporter-2 inhibitors (SGLT2is) (3.08; 2.37-3.99), angiotensin receptor/neprilysin inhibitors [ARNis] (1.84; 1.45-2.35) and mineralocorticoid receptor antagonists (MRAs) (1.41; 1.11-1.8) than patients receiving routine care alone.
Conclusions: Access to embedded interdisciplinary HF teams within community cardiology practices was associated with improved GDMT prescribing, supporting broader adoption of interdisciplinary care models for optimizing GDMT.
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http://dx.doi.org/10.1016/j.cardfail.2025.01.029 | DOI Listing |
BMJ Ment Health
September 2025
Independent Researcher, Cardiff, Cardiff, UK
Background: Mental health research has long been structured around qualitative and quantitative methodologies, often marginalising experiential knowledge and reinforcing hierarchies of expertise. Although coproduction has gained traction as a participatory approach, its methodological status remains contested, leading to inconsistent practices and risks of tokenism.
Objective: This paper explores whether coproduction should be recognised not merely as a participatory ideal but as a third methodological pillar in mental health research, with distinct philosophical, ethical and practical foundations.
Disabil Rehabil Assist Technol
September 2025
School of Drama, Film and Television, Shenyang Conservatory of Music, Shenyang, China.
This study examines how choral singing functions as a mechanism for sustaining ritual practice and reinforcing cultural identity. By integrating perspectives from musicology, social psychology, and cognitive science, it explores how collective vocal performance supports emotional attunement, group cohesion, and symbolic memory in culturally diverse contexts. A mixed-methods approach was applied, combining ethnographic observation, survey-based data, and cognitive measures with AI-informed frameworks such as voice emotion recognition and neural synchrony modeling.
View Article and Find Full Text PDFNano Lett
September 2025
School of Materials Science and Engineering, Peking University, Beijing 100871, People's Republic of China.
High-density mirror twin boundaries (MTBs) embedded in two-dimensional (2D) transition metal dichalcogenides (TMDCs) have emerged as fascinating platforms for exploring charge density wave and Tomonaga-Luttinger liquid-related issues. However, the reversible manipulation of high-density MTBs in 2D TMDCs remains challenging. Herein, we report the first fabrication of high-density MTB loops in ultrathin 1T-NiTe on the SrTiO(001) substrate, by postannealing as-grown 1T-NiTe under Te-deficient conditions.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
College of Chemistry and Chemical Engineering, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha 410081, China.
The oxygen evolution reaction (OER) in conventional zinc-air batteries (ZABs) involves a complex multielectron transfer process, leading to slow reaction kinetics, high charging voltage, and low energy efficiency. To address these limitations, a zinc-ethanol/air battery (ZEAB) system that strategically replaces the OER with the ethanol oxidation reaction (EOR) possessing a lower thermodynamic potential has been proposed. Herein, a bimetallic catalyst CuCo-embedded nitrogen-doped carbon (CuCo-20%-1), derived from a Cu/Co/Cd co-coordinated metal-organic precursor, is synthesized and exhibits an excellent performance for both EOR and ORR.
View Article and Find Full Text PDFNanomicro Lett
September 2025
Nanomaterials & System Lab, Major of Mechatronics Engineering, Faculty of Applied Energy System, Jeju National University, Jeju, 63243, Republic of Korea.
Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring, clinical diagnosis, and robotic applications. Nevertheless, it remains a critical challenge to simultaneously achieve desirable mechanical and electrical performance along with biocompatibility, adhesion, self-healing, and environmental robustness with excellent sensing metrics. Herein, we report a multifunctional, anti-freezing, self-adhesive, and self-healable organogel pressure sensor composed of cobalt nanoparticle encapsulated nitrogen-doped carbon nanotubes (CoN CNT) embedded in a polyvinyl alcohol-gelatin (PVA/GLE) matrix.
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