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Advanced ovarian serous carcinoma presents significant surgical challenges due to tumor size, deep location, and complex anatomical relationships with surrounding structures. This case report highlights the use of 3D printing technology to improve surgical planning and outcomes in such complex scenarios. A 48-year-old female presented with bilateral ovarian tumors, confirmed as serous cystadenocarcinoma. Preoperative 3D modeling was employed to create a detailed anatomical model based on imaging data. This model provided precise visualization of tumor size, vascular supply, and relationships with adjacent organs, facilitating the development of an optimal surgical plan. During surgery, bilateral ovarian tumors were resected along with the uterus, omen tum, and lymph nodes, achieving complete R0 resection. Postoperatively, the patient recovered well, with no complications or recurrence observed during follow-up. This case underscores the value of 3D printing in enhancing surgical precision and safety in complex gynecological oncology cases. By providing individualized anatomical insights, 3D printing supports preoperative planning, improves patient outcomes, and contributes to advancing precision medicine in surgical practice.
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http://dx.doi.org/10.3389/fonc.2025.1541919 | DOI Listing |
Nanomicro Lett
September 2025
Department of Mechanical, Aerospace & Biomedical Engineering, University of Tennessee, Knoxville, Knoxville, TN, 37996, USA.
3D printing, as a versatile additive manufacturing technique, offers high design flexibility, rapid prototyping, minimal material waste, and the capability to fabricate complex, customized geometries. These attributes make it particularly well-suited for low-temperature hydrogen electrochemical conversion devices-specifically, proton exchange membrane fuel cells, proton exchange membrane electrolyzer cells, anion exchange membrane electrolyzer cells, and alkaline electrolyzers-which demand finely structured components such as catalyst layers, gas diffusion layers, electrodes, porous transport layers, and bipolar plates. This review provides a focused and critical summary of the current progress in applying 3D printing technologies to these key components.
View Article and Find Full Text PDFJ Surg Oncol
September 2025
Department of Orthopedic Surgery, McGill University Health Centre, Montreal, Québec, Canada.
Introduction: Three-dimensional printing (3DP) technology has increasingly gained attention in orthopedic oncology, where complex tumor resections and reconstructions demand high precision. 3DP enables the creation of patient-specific models and prostheses, which can improve postoperative quality of life for patients while assisting surgeons in preoperative planning, enhancing surgical accuracy, and improving outcomes in complex oncologic cases. Despite its potential, comprehensive data on the effectiveness and applications of 3DP in orthopedic oncology are limited.
View Article and Find Full Text PDFAdv Mater
September 2025
Departmant of Materials Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea.
Microrobots are expected to push the boundaries of robotics by enabling navigation in confined and cluttered environments due to their sub-centimeter scale. However, most microrobots perform best only in the specific conditions for which they are designed and require complete redesign and fabrication to adapt to new tasks and environments. Here, fully 3D-printed modular microrobots capable of performing a broad range of tasks across diverse environments are introduced.
View Article and Find Full Text PDFAdv Mater
September 2025
Beijing Advanced Innovation Center for Soft Matter Science and Engineering, State Key Laboratory of Organic-Inorganic Composites, Bionanomaterials & Translational Engineering Laboratory, Beijing Key Laboratory of Bioprocess, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical
Sonocatalytic therapy (SCT) is a non-invasive tumor treatment modality that utilizes ultrasound (US)- activated sonocatalysts to generate reactive oxygen species (ROS), whose production critically dependent on the electronic structural properties of the catalytic sites. However, the spin state, which is a pivotal descriptor of electronic properties, remains underappreciated in SCT. Herein, a Ti-doped zirconium-based MOF (Ti-UiO-66, denoted as UTN) with ligand-deficient defects is constructed for SCT, revealing the important role of the electronic spin state in modulating intrinsic catalytic activity.
View Article and Find Full Text PDFCureus
August 2025
Cardiovascular Medicine, Moscow Multidisciplinary Clinical Center Kommunarka, Moscow, RUS.
Simulation-based training is transforming the education of vascular surgeons in the management of aortic aneurysms (AAs), addressing limitations in traditional apprenticeship models amid declining open surgical volumes and increasing reliance on complex endovascular techniques. This review explores the current landscape of simulation technologies, including computational modeling, fluid-structure interaction, patient-specific 3D printing, artificial intelligence, and robotic platforms. These tools enable high-fidelity, anatomically accurate, and physiologically realistic training environments.
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