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Background: Previous studies have explored the perspectives of health care professionals on the use of medicinal hemp, but they were mostly situated in high income countries. This study sets out to investigate the knowledge, attitudes, and beliefs of health care professionals regarding the use of hemp in clinical therapy vis-à-vis the legislative framework in Ghana.
Objective: To explore the perspectives of physicians on the use of medicinal hemp and its legalization in Ghana.
Method: A qualitative study employing purposive sampling and face-to-face in-depth interviews was conducted among twenty (20) physicians practicing in Ghana. The interviewees were selected based on specialty and scope of practice. The in-depth interviews were audio recorded, transcribed, and thematically analyzed using the Theory of Planned Behavior.
Results: Twenty (20) clinicians participated in the study. Fourteen (14) respondents were male and six (6) were female. The medical specialties of the interviewees were anaesthesiology, oncology, neurology, and orthopaedics. The identified themes include clinical use, stigma (sociocultural classification of cannabis), clinical non-prescription, policy landscape and regulatory control.
Conclusion: Prescribers' intention to recommend medicinal hemp is influenced by a complex interplay of various socio-political factors such as knowledge, policy, cultural environment, and stigma.
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http://dx.doi.org/10.1186/s42238-025-00271-1 | DOI Listing |
Biomed Pharmacother
September 2025
Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, University of Seville, Spain; Instituto de Biomedicina de Sevilla, IBiS/Hospital Universitario Virgen del Rocio/CSIC/Universidad de Sevilla, Seville, 41013, Spain. Electronic address:
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive impairment, synaptic dysfunction, and neuronal loss. Neuroinflammation, driven by the activation of microglia and astrocytes, is a key contributor to AD pathology, amplifying oxidative stress and amyloid-β toxicity. Modulation of neuroinflammatory pathways thus represents a promising therapeutic strategy.
View Article and Find Full Text PDFInjury
August 2025
Institute for Research in Military Medicine (IRMM), Faculty of Medicine, The Hebrew University of Jerusalem and the Israel Defense Forces Medical Corps, Jerusalem, Israel; Department of Military Medicine ("Tzameret"), Faculty of Medicine, The Hebrew University of Jerusalem, and the Israel Defense Fo
Background: Hemorrhage remains the principal cause of death on the battlefield. It is suggested that Tranexamic acid (TXA) can improve survival of severely-bleeding casualties. The intravenous approach is not always available in the pre-hospital setting.
View Article and Find Full Text PDFDrug Alcohol Depend
August 2025
Department of Psychiatry, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address:
Background: Alcohol and cannabis co-use is increasingly prevalent across the U.S., concomitant with trends towards recreational cannabis legalization.
View Article and Find Full Text PDFPsychopharmacology (Berl)
September 2025
Center for Medicinal Cannabis Research, Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
Rationale: Between periods of use, chronic cannabis consumers may display residual effects on selective cognitive functions, particularly memory and attention. Whether there are comparable deficits in real-world behaviors, such as driving, has not been thoroughly examined.
Objectives: The current study explored the association between driving simulator performance, cannabis use history, and demographic factors after ≥ 48 h of abstinence.
Drug Alcohol Depend
August 2025
Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Anesthesiology, School of Medicine, University of Virginia, Charlottesville, VA, USA.
Background: Craving is an aversive state and risk factor for progression to nonmedical substance use. The aims of this secondary analysis of Ecological Momentary Assessment (EMA) data were 1) to test whether craving was elevated on days of co-use of opioids and cannabis, and 2) to examine pain, pain catastrophizing, affect, and stress as risk factors for current and next-moment craving, among patients with chronic pain.
Methods: Adults with chronic pain (N = 46) who used both opioids and cannabis were recruited online and completed a 30-day EMA study, consisting of four momentary surveys per day that assessed opioids and cannabis craving, use, pain and pain catastrophizing, affect, and stress.