Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Purpose: To compare the functional and aesthetic outcomes of two surgical techniques used to correct severe congenital ptosis with poor levator function (LF): frontalis muscle (FM) flap advancement and frontalis sling (FS) surgery.

Methods: This prospective interventional randomized comparative study included 42 eyelids of 34 children with severe congenital ptosis and poor LF. The children were randomly divided into two groups, with 21 eyelids of 19 patients undergoing FM flap advancement, and 21 eyelids of 15 patients undergoing FS surgery. The follow-up period was 6 months.

Results: At 6 months' follow-up, both groups showed comparable improvement in margin reflex distance 1 (MRD1) (3 ± 1.7 vs 3 ± 1.5 mm). Eyelid contour was satisfactory in 91% of flap and 76% of sling procedures. Lid crease was satisfactory in 95% of flap and 81% of sling procedures (P = 0.41 and 0.34, resp.). Complications in flaps included hematoma (38%), eyelid "pop" (10%), lash ptosis (10%), and lagophthalmos (5%); in slings, infection (10%). Undercorrection rates and recurrence rates did not differ significantly between flap (24% and 14%, resp.) and sling groups (19% and 24%, resp.).

Conclusions: In our study cohort, FM flap advancement yielded comparable results to those of conventional FS surgeries for correcting congenital ptosis with poor LF in children.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaapos.2025.104180DOI Listing

Publication Analysis

Top Keywords

flap advancement
16
congenital ptosis
12
ptosis poor
12
frontalis sling
8
severe congenital
8
poor children
8
eyelids patients
8
patients undergoing
8
sling procedures
8
flap
6

Similar Publications

Smartphone-assisted colorimetric detection of FEN1 and its inhibitors via RCA-magnetic beads-urease cascade amplification.

Biosens Bioelectron

September 2025

College of Pharmacy, Xinjiang Key Laboratory of Biopharmaceuticals and Medical Devices, Xinjiang Medical University, Urumqi, 830017, China; State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy

Given the pivotal role of Flap endonuclease 1 (FEN1) in tumor pathogenesis and progression, the advancement of its activity and inhibitor assays holds significant importance for cancer research and drug screening. Herein, we proposed a convenient, visual and sensitive colorimetric biosensing platform for FEN1 activity detection by integrating the robust signal amplification power of rolling circle amplification (RCA), the target enrichment capability of magnetic beads (MB), and the high efficiency and visualization of urease-mediated litmus test. Based on the significant color transition with a clear response mechanism, quantitative analysis can be achieved by either spectroscopic or smartphone-based detection.

View Article and Find Full Text PDF

Objectives: This study aimed to compare the efficacy of the full-thickness palatal graft technique (FTPGT) and the coronally advanced flap with subepithelial connective tissue graft (CAF + SCTG) in achieving complete root coverage (CRC) in single gingival recessions (GR).

Methods: Forty healthy patients with a single RT1 GR were randomized into two groups: 20 treated with CAF + SCTG and 20 with FTPGT. Baseline and 12-month measurements of GR, keratinized tissue width (KTW), probing depth (PD), clinical attachment level (CAL), and gingival thickness (GT) were recorded.

View Article and Find Full Text PDF

Utilizing biomaterials for laryngeal respiratory mucosal tissue repair in an animal model.

Biomater Biosyst

September 2025

ENT and Head and Neck Research Center and Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Introduction: The airway mucosa plays a crucial role in protection and various physiological functions. Current methods for restoring airway mucosa, such as myocutaneous flaps or split skin grafts, create a stratified squamous layer that lacks the cilia and mucus-secreting glands of the native columnar-lined airway. This study examines the application of various injectable biopolymers as active molecules for a potential approach to regenerating laryngeal epithelial tissue.

View Article and Find Full Text PDF

Differences in the Corneal Biomechanical Responses to LASIK and KLEx Based on Parametric Numerical Simulation.

J Refract Surg

September 2025

From National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.

Purpose: To use parametric numerical simulation to characterize and compare the differences in corneal biomechanical responses to laser in situ keratomileusis (LASIK) and keratorefractive lenticule extraction (KLEx) under various surgical settings.

Methods: The Finite Element Model was used in a parametric study to evaluate corneal biomechanical responses to LASIK and KLEx, considering variations in preoperative corneal thickness, corneal flap/cap thickness and diameter, refractive correction, and optical zone diameter. Surgery-induced stress, displacement, and interface contact pressure were compared between LASIK and KLEx using the Wilcoxon signed-rank test.

View Article and Find Full Text PDF

The advancement of science and technology is an undeniable phenomenon that is progressively transforming all aspects of human life, including scientific, social, humanitarian, and environmental fields, among others. Facial reconstruction surgery has recently gained much attention owing to the incorporation of new technologies, such as bioprinting, regenerative medicine (RM), and artificial intelligence (AI) in surgery. These advancements have led to more innovative, site-specific, and optimal methods of addressing the challenges of facial reconstruction following trauma, congenital malformations, and oncological resections.

View Article and Find Full Text PDF