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This study aimed to conduct a comparative epidemiological survey of uveitis across various healthcare settings and elucidate the clinical characteristics. We conducted a retrospective cross-sectional study in the Ube-City medical region in Yamaguchi prefecture and recruited 268 patients from a university hospital (151 patients), municipal hospitals (51 patients), and private eye clinics (58 patients). Medical records of patients newly diagnosed with uveitis between January 2018 and December 2019 in the institutes were included, reviewed, and compared. The main outcomes included the number of uveitis causes, treatment methods, and visual acuity. Panuveitis, which is associated with systemic diseases, such as Vogt-Koyanagi-Harada disease and sarcoidosis, was more prominent in university hospital patients. Conversely, anterior uveitis, including traumatic iritis, was prominently detected in general hospitals and private eye clinics. The best-corrected visual acuity improved to 1.0 (logMAR = 0); an improvement of 74%, 61%, and 54% was observed in private eye clinic, general hospital, and university hospital patients, respectively. This study identified differences in uveitis presentation and treatment across diverse clinical settings. The results of this study provide valuable data for differentiating the causes of uveitis at university hospitals, general hospitals, and private eye clinics.
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http://dx.doi.org/10.1038/s41598-025-93223-x | DOI Listing |
Ophthalmic Plast Reconstr Surg
September 2025
Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, California, U.S.A.
Purpose: To evaluate the efficacy and safety of teprotumumab for the treatment of thyroid eye disease in geriatric patients.
Methods: This was a multicenter cohort study of patients aged 75 and older, treated between February 2020 and September 2023 across 10 tertiary institutions. Patients were included if they had moderate-to-severe thyroid eye disease and at least 1 infusion of teprotumumab.
J Cataract Refract Surg
September 2025
Altos Eye Physicians, Los Altos, CA, USA.
Purpose: To quantify and compare the cost, waste, and carbon emissions of single-use and reusable phacoemulsification tubing/cassettes and knives.
Setting: Private, single-specialty ambulatory surgery center (Mountain View, CA, USA).
Design: Retrospective data review.
Am J Ophthalmol
September 2025
Dean McGee Eye Institute, University of Oklahoma, Oklahoma City, Oklahoma, USA. Electronic address:
Purpose: To compare refractive prediction accuracy using simulated keratometry (SimK) measurements obtained from a Scheimpflug tomographer (Pentacam AXL, Oculus) versus keratometry (K) measurements obtained from an optical biometer utilizing telecentric keratometry (IOLMaster 700 (IOLM700), Carl Zeiss Meditec AG) applied to modern IOL power calculation formulas.
Design: Retrospective accuracy and validity analysis METHODS: Setting: Private practice center STUDY POPULATION: Five hundred eighty-nine eyes with preoperative SimK and K measurements undergoing phacoemulsification and implantation of monofocal IOL (Clareon SY60WF IOL, Alcon Laboratories, Inc.).
Adv Ther
September 2025
Centre d'Ophtalmologie Visis, 66000, Perpignan, France.
Introduction: Glaucoma treatment predominantly involves the use of topical anti-glaucoma eye drops, with patient adherence influenced by individual preferences. This study aimed to assess these preferences and highlight the importance of personalized treatment approaches among ophthalmologists.
Methods: This French multicenter, cross-sectional study involved 21 ophthalmologists-members of the Board of Directors of the French Society of Glaucoma-from both public and private practices, who distributed a standardized questionnaire to their patients with glaucoma.
PLOS Digit Health
September 2025
Singapore Health Services, Artificial Intelligence Office, Singapore.
Large Language Models (LLMs) show promise in augmenting digital health applications. However, development and scaling of large models face computational constraints, data security concerns and limitations of internet accessibility in some regions. We developed and tested Med-Pal, a medical domain-specific LLM-chatbot fine-tuned with a fine-grained, expert curated medication-enquiry dataset consisting of 1,100 question and answer pairs.
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