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Article Abstract

Summary: AlphaPulldown2 streamlines protein structural modeling by automating workflows, improving code adaptability, and optimizing data management for large-scale applications. It introduces an automated Snakemake pipeline, compressed data storage, support for additional modeling backends like UniFold and AlphaLink2, and a range of other improvements. These upgrades make AlphaPulldown2 a versatile platform for predicting both binary interactions and complex multi-unit assemblies.

Availability And Implementation: AlphaPulldown2 is freely available at https://github.com/KosinskiLab/AlphaPulldown.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937959PMC
http://dx.doi.org/10.1093/bioinformatics/btaf115DOI Listing

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