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Bitterness and off-flavors are problematic in some citrus genotypes, particularly hybrids with in their pedigrees that have shown tolerance to the devastating citrus greening disease. Comprehensive chemical profiling combined with sensory analysis of bitterness were used to determine bitter compounds in citrus juice. A selection of genotypes including orange, grapefruit, pummelo, tangelo, mandarin hybrids with and without in their pedigrees, as well as pure were analyzed due to their broad range in bitterness intensity. Widely targeted LC-MS/MS analysis of flavonoids and limonoids confirmed the role of limonin, nomilin, neohesperidin and poncirin in bitterness perception. Other flavonoids, mainly rhoifolin, apigenin, and tricin also correlated with bitterness. Notably, rhoifolin was more strongly correlated with bitterness than the previously known bitter compounds. Identifying the compounds that contribute to bitterness in citrus is a crucial first step for future breeding efforts aimed at reducing these compounds biosynthetically.
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http://dx.doi.org/10.1016/j.fochx.2025.102289 | DOI Listing |
Crit Rev Food Sci Nutr
September 2025
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, P. R. China.
Natural products have emerged as a vital source of active ingredients in medicine, food, and cosmetics due to their unique biological activities, safety profiles, and sustainability. However, most bioactive compounds in natural products are intensely bitter, limiting their use in pharmaceuticals and foods. The bitter taste attributes vary markedly among different compound classes, predominantly due to their structural characteristics.
View Article and Find Full Text PDFCurr Atheroscler Rep
September 2025
Department of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, 521 19th Street South-GSB 444, Birmingham, AL, 35233, USA.
Purpose Of Review: This review examines cardiovascular disease (CVD) risk prediction models relevant to older adults, a rapidly expanding population with elevated CVD risk. It discusses model characteristics, performance metrics, and clinical implications.
Recent Findings: Some models have been developed specifically for older adults, while several others consider a broader age range, including some older individuals.
Compr Rev Food Sci Food Saf
September 2025
School of Molecular and Life Sciences, Faculty of Science and Engineering, Curtin University, Bentley, Western Australia, Australia.
Introducing underutilized legumes as plant-based protein sources to daily meals is an approach to address the increasing demand for alternative proteins. However, legumes often exhibit off-flavors and aromas, causing negative consumer perceptions. Lupins are an underutilized legume that is becoming popular as a plant protein source due to their high protein, fiber, and low starch contents.
View Article and Find Full Text PDFFood Res Int
November 2025
Jilin Provincial Key Laboratory of Nutrition and Functional Food, Jilin University, Changchun 130062, People's Republic of China; College of Food Science and Engineering, Jilin University, Changchun 130062, People's Republic of China. Electronic address:
Egg white peptides (EWPs) face significant flavor challenges due to bitterness, limiting their high-value applications. This study prepared egg white glycopeptides (EWGP) through transglutaminase-catalyzed glycosylation to investigate their flavor enhancement effect. Egg white protein was hydrolyzed by neutral protease and covalently bound to glucosamine under the mediation of transglutaminase to obtain EWGP.
View Article and Find Full Text PDFFood Res Int
November 2025
Department of Food and Drug, University of Parma, Viale Parco Area delle Scienze, 43124 Parma, Italy; Institute of Biophysics, National Research Council (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.
The hop plant is gaining interest in the food, pharmaceutical, and cosmetics industries due to its abundance of secondary metabolites. However, branches and leaves, despite their antioxidant potential, are typically discarded. To valorize these components as functional ingredients they were dried, milled into hop powder (HP), and used to enrich bread.
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