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Background: Pierre Robin sequence (PRS) is characterized by micrognathia, glossoptosis, and upper airway obstruction. This study aimed to compare the dentoskeletal characteristics of children diagnosed with non-syndromic PRS and those with cleft palate.
Methods: This study was conducted on the non-syndromic PRS patients in the database of our hospital. The control group of non-syndromic isolated incomplete cleft palate patients was matched from the same database by age, gender and weight in a 1:3 ratio. The dentoskeletal characteristics were compared between the PRS and control groups.
Results: The study included 14 patients in the PRS group and 42 patients in the control group. A point-Nasion-B point (ANB) angle was significantly greater in the PRS group compared with the control group. The PRS group exhibited a significantly lower ratio of the linear distance between Articulare and Gonion (ArGo) to the distance between Gonion and Pogonion (GoPo) compared to the control group. Additionally, the anteroposterior length and area of the lower pharyngeal airway space (LPAS) were markedly reduced in the PRS group.
Conclusion: The ANB angle, the ArGo/GoPO ratio and the anteroposterior length and area of LPAS could serve as valuable indicators to identify micrognathia in patients with non-syndromic PRS.
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http://dx.doi.org/10.3389/fped.2025.1519266 | DOI Listing |
Crit Rev Immunol
January 2025
Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Galectin-10(Gal-10)/CLC(Charcot-Leyden crystal) has been discovered to be related to ECRSwNP characterized by high eosinophilic infiltration. We aimed to investigate the effects of Gal-10 on ECRSwNP. A total of 36 tissue samples were collected, including 11 ECRSwNP samples, 15 non-ECRSwNP samples, and 10 Control samples.
View Article and Find Full Text PDFJ Environ Pathol Toxicol Oncol
January 2025
Department of Biostatistics, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Prostate cancer and inflammation mechanism are closely related because chronic inflammation causes inflammatory cells to infiltrate into prostatic atrophy areas and proliferative inflammatory atrophy is accepted as the initiator of prostate cancer. The study included 90 patients (28 patients with benign prostatic hyperplasia (BPH), 35 patients with localized prostate cancer (LPCa), and 27 patients with metastatic prostate cancer (MPCa) and 90 healthy controls. Blood samples from 90 patients and 90 healthy people were used to isolate genomic DNA.
View Article and Find Full Text PDFEur J Oncol Nurs
August 2025
Koç University Hospital, Faculty of Medicine, Department of Medical Oncology, Istanbul, Türkiye. Electronic address:
Purpose: This study aimed to evaluate the effectiveness of a mobile chemotherapy drug guide application, ChemoNurse, developed for cancer nurses, in improving their knowledge and attitudes toward chemotherapy practices.
Methods: A randomized controlled trial with a repeated-measures design was conducted with 59 nurses (29 intervention, 30 control) who participated. Nurses in the intervention group used the ChemoNurse mobile application for six months, while the control group received no additional intervention.
J Med Internet Res
September 2025
School of Governance and Policy Science, The Chinese University of Hong Kong, Hong Kong, China (Hong Kong).
Background: Older adults are more vulnerable to severe consequences caused by seasonal influenza. Although seasonal influenza vaccination (SIV) is effective and free vaccines are available, the SIV uptake rate remained inadequate among people aged 65 years or older in Hong Kong, China. There was a lack of studies evaluating ChatGPT in promoting vaccination uptake among older adults.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health & Life Science Institute, Guangxi Medical University, Nanning, China.
Background: The 23-valent pneumococcal polysaccharide vaccine reduces the risk of pneumonia among adults by 38% to 46%. However, only a few older adults in resource-limited areas of China have received the pneumococcal vaccination. Pay-it-forward is a social innovation that offers participants free or subsidized health services and a community-engaged message, with an opportunity to donate to support subsequent recipients.
View Article and Find Full Text PDF