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Aim: This study aimed to assess dentists' perceptions and knowledge of plasma-rich protein and uses in rate of tooth movement.
Material And Methods: This online survey, which is cross-sectional in nature, is being done among dental care providers. The 500 participants' self-administered questionnaires on PRP in orthodontic tooth mobility. The statistical analysis was performed using the Statistical Package for Social Sciences (SPSS) (V 22.0). The frequency distribution was calculated.
Results: The survey revealed that, 452 (90.4%) were aware of the PRP preparation process, and 400 (20%) were aware of the use of plasma-rich protein (PRP) to accelerate tooth movement. Regarding the primary PRP ingredients and the PRP procedure for quickening tooth movement in orthodontics, 66.4% had given the right responses. The majority of dentists were sufficiently knowledgeable about both invasive and non-invasive methods for quickening the movement of teeth.
Conclusion: The study's conclusions demonstrated that dental professionals were aware of the most recent developments in dental PRP application and its protocols, but additional research has to be done to educate everyone about these recent developments. Future experimental research on PRP in dental practices will be necessary in order to further develop our awareness of it.
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http://dx.doi.org/10.4103/jpbs.jpbs_1145_24 | DOI Listing |
Sci Rep
August 2025
Department of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Cancer treatments can lead to infertility, particularly in prepubertal boys who cannot preserve sperm before therapy. In vitro spermatogenesis offers a promising strategy for fertility preservation in this population by enabling the development of sperm from immature testicular tissue under controlled conditions. This study investigates the effects of a novel culture medium containing plasma rich in growth factors (PRGF) and knockout serum replacement (KSR) on in vitro spermatogenesis.
View Article and Find Full Text PDFJ Ocul Pharmacol Ther
August 2025
Department of Ophthalmology, Luzerner Kantonsspital, Lucerne, Switzerland.
To analyze the effect of fasting on volume, growth factor, and lipid concentration in eye drops derived from autologous serum (AS) and leukocyte-poor platelet-rich plasma (LP-PRP). To assess changes in protein and growth factor concentration after filtration with three different syringe filters and after complement inactivation with heat. Blood samples from 10 volunteers after a fasting and nonfasting period were harvested on two separate visits.
View Article and Find Full Text PDFACS Synth Biol
August 2025
Christian Doppler Laboratory for Innovative Immunotherapeutics, BOKU University, Muthgasse 18, 1190 Vienna, Austria.
Peptide libraries present have improved means to effectively identify epitopes of antibodies, either as monoclonal reagents or polyclonal constituents of the immune response, which includes characterization of vaccination responses, profiling of allergic reactions, and screening of patient samples for autoantibodies. In all of these examples, there is an urgent demand for simple and inexpensive target epitope screening. Here, we present a method for epitope identification, based on the yeast display of overlapping peptides conformationally constrained within the capsid protein PP7 with the aid of a disulfide bridge.
View Article and Find Full Text PDFAdv Sci (Weinh)
July 2025
Department of Plastic Surgery, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, China.
Diabetic wound is a significant clinical challenge, and stem cell therapy has shown great potential. This study explores the role of mesenchymal stem cell (MSC) spheroids (Sp-MSCs) in healing diabetic wounds and the use of autologous plasma-rich platelet fibrin (PRF) as a scaffold for Sp-MSCs. Through activation of the coagulation system, PRF offers a protective fibrin shield for Sp-MSCs to promote the rapid recovery migration and proliferation of MSCs while maintaining the activity of Sp-MSCs in an inflammatory overload environment by activating the related genes of Integrin-β1-vascular endothelial growth factor (VEGF), and Wnt/β-catenin pathways.
View Article and Find Full Text PDFSmall
May 2025
Laoshan Laboratory, 168 Wenhai Middle Road, Qingdao, Shandong, 266237, China.
Infertility resulting from uterine damage has emerged as a significant challenge confronting the development of modern society. Existing therapeutic approaches frequently encounter limitations due to the intricate physical and physiological environment of uterus. Platelet-rich plasma (PRP), a concentrate of platelets enriched with various growth factors, has been used in uterine injury repair.
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