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http://dx.doi.org/10.1200/OP-24-00953 | DOI Listing |
J Cancer Surviv
September 2025
Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Purpose: Cancer-related cognitive impairment (CRCI) adversely affects cancer survivors' academic, occupational, and psychosocial functioning. Analyzing the National Institutes of Health (NIH) portfolio of funded research provides insight into current efforts, trends, and gaps in CRCI research.
Methods: We queried the internal NIH iSearch database to identify awards focused on CRCI.
Am J Phys Med Rehabil
August 2025
Department of Rehabilitation, The First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Purpose: The aim of this umbrella review is to assess the effectiveness of exercise interventions in preventing and managing cancer-related cognitive impairment among cancer survivors, providing an evidence-based foundation for clinical practice.
Methods: The umbrella review was pre-registered on PROSPERO. It included systematic reviews that assessed any exercise interventions aimed at improving cognition in cancer patients.
J Natl Cancer Inst
September 2025
Centre Francois Baclesse, Medical oncology department, University UniCaen, Anticipe U1086 Inserm, Caen, France.
Background: Breast cancer (BC) survivors receiving adjuvant treatments often report clinically relevant cancer-related cognitive complaints (CRCC), which have a significant impact on quality of life. We aimed to develop a comprehensive model of prediction of CRCC, including clinical and serum inflammatory protein data.
Methods: We included 9575 stage I-III BC patients from the CANTO cohort (NCT01993498).
J Sex Res
September 2025
Department of Oncology, Division of Psychosocial Oncology, Cumming School of Medicine, University of Calgary.
Mindfulness-based cognitive therapy (MBCT) and supportive-expressive sex education therapy (STEP) are effective group treatments for sexual dysfunction after breast cancer (BrCa). We explored mediators and moderators of outcomes following the 8-week groups. BrCa survivors ( = 116, mean age = 49.
View Article and Find Full Text PDFDiscov Oncol
September 2025
Department of Biochemistry, Kampala International University, Ishaka, Uganda.
Neurophysiological alterations represent a growing concern in oncology, affecting both the central and peripheral nervous systems through diverse mechanisms. These include direct tumor infiltration, paraneoplastic immune responses, systemic inflammation, metabolic dysregulation, and treatment-induced neurotoxicity. Neurological complications range from cognitive impairment and peripheral neuropathy to motor deficits and autonomic dysfunction.
View Article and Find Full Text PDF