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Background: Complications following total hip arthroplasty (THA) may necessitate a revision and patients who go on to a revision THA may experience depressive symptoms. The objective of this study was to investigate the prevalence of depressive symptoms before and after revision THA for six different failure modes.
Methods: Patients who underwent a THA revision with minimum 1-year follow-up at a single institution from 2008 to 2022 were retrospectively reviewed. Patients were grouped by failure modes: aseptic loosening, impingement, infection, instability, metallosis, polyethylene wear, and femoral stem pain. Preoperative and postoperative Veterans RAND 12-Item Health Scores and Harris Hip Score were compared.
Results: Twenty-four percent of patients in the retrospective cohort review had a previous existing mental health diagnosis, with depression being the most common (18% of all patients). The prevalence of depressive symptoms differed significantly by failure mode both preoperatively ( = .002) and postoperatively ( = .019). Veterans RAND 12 mental component score was significant between mode of failure groups both preoperatively ( < .001) and postoperatively ( = .005). Function significantly improved in all groups from preoperatively to postoperatively. Patients with depressive symptoms had significantly lower physical component score with instability, aseptic loosening, stem pain, and metallosis preoperatively ( < .001) and with instability, aseptic loosening, stem pain, and polyethylene wear postoperatively ( = .002).
Conclusions: Nearly 25% of patients with failed THA had a pre-existing mental health diagnosis and depressive symptoms were the most common. Unfortunately, depressive symptoms only improve modestly with revision surgery and can adversely affect a patient's functional outcome.
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http://dx.doi.org/10.1016/j.artd.2025.101627 | DOI Listing |
JAMA Netw Open
September 2025
Department of Social Epidemiology, Graduate School of Medicine and School of Public Health, Kyoto University, Kyoto, Japan.
Importance: Previous studies have suggested that social participation helps prevent depression among older adults. However, evidence is lacking about whether the preventive benefits vary among individuals and who would benefit most.
Objective: To examine the sociodemographic, behavioral, and health-related heterogeneity in the association between social participation and depressive symptoms among older adults and to identify the individual characteristics among older adults expected to benefit the most from social participation.
Child Psychiatry Hum Dev
September 2025
Department of Psychology, University of California, Los Angeles, CA, USA.
Youth anxiety and depression are rising rapidly worldwide, highlighting the need for efficient school-based assessment tools across sociocultural contexts. The Revised Child Anxiety and Depression Scale (RCADS) is one of the most widely used screening measures, with demonstrated cross-cultural applicability. However, its psychometric properties have rarely been evaluated in Chinese populations.
View Article and Find Full Text PDFEnviron Sci Process Impacts
September 2025
NMPA Key Laboratory for Safety Evaluation of Cosmetics, Guangdong Provincial Key Laboratory of Tropical Disease Research, Department of Toxicology, School of Public Health, Southern Medical University, 1023-1063 Shatai Nan Road, Guangzhou 510515, China.
Triclosan (TCS) has raised concerns due to its widespread use and potential neuroendocrine toxicity. However, its neurological effects and the interplay between TCS-induced sex hormone disruption and neurological outcomes in adults remain largely unexplored. Herein, we analyzed data from 2717 adults in the 2011-2014 National Health and Nutrition Examination Survey, employing logistic regression, restricted cubic spline, and mediation analyses to investigate the association between TCS exposure and neurological outcomes.
View Article and Find Full Text PDFAging Ment Health
September 2025
Department of Psychology, University of California, Irvine, CA, USA.
Objectives: Being socially integrated is vital to emotional well-being, partly because social connections provide purpose. Nevertheless, fewer have explored purpose in life as a potential mechanism linking social activity variety, one of the indicators of social integration, to mental health outcomes. This study examined purpose in life as a mediator in the relationship between earlier social activity variety and later depressive symptoms among U.
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