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| http://dx.doi.org/10.1152/ajpgi.00053.2025 | DOI Listing |
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Patent ductus venosus is a congenital portosystemic shunt that may cause progressive portal hypertension, hepatic encephalopathy, and focal nodular hyperplasia of the liver. Embolization of the Arantius' duct is the first choice of treatment in infants and children. However, it carries the risk of coil migration into the systemic circulation in adult patients with larger Arantius ducts.
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View Article and Find Full Text PDFCombined inflation and cooling method improves lung function in uncontrolled donation after circulatory death.
J Thorac Cardiovasc Surg
September 2025
Department of General Thoracic and Breast and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. Electronic address:
Objective: Currently, the two methods used to preserve lungs from uncontrolled donation after circulatory death-topical cooling and inflation-result in the suboptimal utilization of lungs. This study aimed to introduce an approach that combines cooling and inflation to investigate whether it improves lung conditions in a swine model, even if the lungs had been damaged with long-term warm ischemia, such as in out-of-hospital cardiac arrest.
Methods: Donor lungs subjected to 1.
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View Article and Find Full Text PDFPlatelet heterogeneity in disease: the many and the diverse?
Blood
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University Hospital, LMU Munich, Munich, Germany.
Platelets in peripheral blood critically drive clot formation in health and disease. Previously considered to uniformly respond to vascular injury and inflammatory cues, recent studies have highlighted that circulating platelets exhibit marked heterogeneity, with distinct populations contributing differentially to hemostasis, thrombosis, and inflammation. In this Review, we highlight platelet diversity as a consequence of origin (i.
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