Cancer in a drop: Liquid biopsy highlights from San Antonio Breast Cancer Symposium (SABCS) 2024.

J Liq Biopsy

Division of Hematology-Oncology, Weill Cornell Medicine, 420 E 70th St, LH 204, New York, NY, 10021, USA.

Published: March 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863971PMC
http://dx.doi.org/10.1016/j.jlb.2025.100286DOI Listing

Publication Analysis

Top Keywords

cancer drop
4
drop liquid
4
liquid biopsy
4
biopsy highlights
4
highlights san
4
san antonio
4
antonio breast
4
breast cancer
4
cancer symposium
4
symposium sabcs
4

Similar Publications

Introduction Stereotactic radiosurgery (SRS) is widely regarded as the standard of care after the resection of brain metastases in order to reduce local cavity recurrence risk. The objective of this study was to explore the reproducibility of published outcomes for patients receiving post-operative stereotactic radiosurgery (cavity SRS) in a National Health Service (NHS) setting for a non-selective series of patients. For our service, the median interval between surgery to cavity SRS (cSRS) is eight weeks, whereas similar timelines have been found to have a deleterious impact on survival in the published literature.

View Article and Find Full Text PDF

Objective: To comprehensively examine the incidence and mortality of malignant neoplasms of bone and articular cartilage (MNBAC) in China compared with the world, as well as its age-specific patterns and sex disparities.

Methods: The MNBAC burden in China and the world was systematically assessed from 1990 to 2021 based on the Global Burden of Disease 2021, including incidence and mortality data. The estimated annual percentage change was calculated.

View Article and Find Full Text PDF

Fenugreek seeds ( L.) are known for their impressive range of health benefits, thanks to their diverse array of phytochemicals. These include steroidal sapogenins like diosgenin, alkaloids such as trigonelline, as well as flavonoids, saponins, galactomannans, and polyphenols.

View Article and Find Full Text PDF

Multiplicity Control in Oncology Clinical Trials With a Binary Surrogate Endpoint-Based Drop-The-Losers Design.

Stat Med

September 2025

Biostatistics and Data Management, Regeneron Pharmaceuticals, Tarrytown, New York, USA.

Typical phase 1 oncology studies identify the maximum tolerated dose as the "optimal" dose for subsequent phases. With the advancement of molecular targeted agents and immunotherapies, however, evaluating two or more doses has become increasingly critical for dose selection. Such evaluation is often done in phase 2 studies in a randomized manner.

View Article and Find Full Text PDF

A nomogram for predicting the risk of chemoradiotherapy-associated thrombocytopenia in patients with esophageal cancer: a real-world cohort study.

Ther Adv Med Oncol

September 2025

Department of Radiation Oncology, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Panjiayuannanli 17#, Beijing 100021, China.

Background: Thrombocytopenia is a common hematological toxicity in esophageal cancer (EC) patients receiving radiation therapy.

Objectives: The purpose of this study was to construct and validate a nomogram for predicting the incidence of thrombocytopenia in EC patients receiving radiotherapy.

Design: A retrospective study.

View Article and Find Full Text PDF