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This study develops a physics-informed neural network (PINN) model to predict stress distribution in a simplified spinal disc structure. The model incorporates 3D spatial inputs and enforces equilibrium conditions through a custom loss function. Trained on synthetic elasticity-based data, it achieves an MAE of 0.026 and an R² of 74.6%. Stress patterns under various loading conditions were visualized, with peak stress occurring at = 1 under top compression. Results demonstrate PINNs' potential for biomechanical modeling, improving predictive accuracy in spinal biomechanics and informing clinical interventions.
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http://dx.doi.org/10.1080/10255842.2025.2471504 | DOI Listing |
J Pain Res
August 2025
Department of Orthopaedics, Xinqiao Hospital of Army Medical University, Chongqing, People's Republic of China.
Purpose: The spinal surgery robot can provide precise preoperative or intraoperative surgical planning and guide the implementation of the surgical plan under real-time navigation monitoring. Researchers have recently begun exploring the use of robotic systems to assist in performing Percutaneous Endoscopic Lumbar Discectomy (PELD). However, prior studies have primarily focused on robotic-assisted transforaminal puncture.
View Article and Find Full Text PDFGlobal Spine J
August 2025
Hospital for Special Surgery, New York, NY, USA.
Study DesignRetrospective cohort study.ObjectiveIn patients with multilevel degenerative lumbar pathology, the decision to extend fusion across all decompressed levels remains a subject of debate. While fusion provides stability in cases of instability or deformity, its necessity for adjacent levels without specific fusion indications is unclear.
View Article and Find Full Text PDFSpine (Phila Pa 1976)
August 2025
Dept. of Spine Surgery, Hospital for Special Surgery, New York, NY.
Study Design: Retrospective review of electronic health records system.
Objective: To compare the indications and complication rates between rhBMP-2 and non-rhBMP-2 use in spine fusion at a high-volume tertiary orthopedic institution.
Summary Of Background Data: Bone morphogenetic proteins are growth factors that play a critical role in bone development and proliferation.
Mult Scler Relat Disord
August 2025
Neuroradiology Section, Radiology Department (IDI), Vall d'Hebron University Hospital, Barcelona, Spain. Electronic address:
Background: MRI is essential for diagnosing and monitoring Multiple Sclerosis. Emerging imaging biomarkers for disease progression often rely on non-conventional MRI sequences and complex post-processing tools, which are not typically available in routine clinical practice.
Aim: To provide radiologists and neurologists worldwide with simplified MRI measurements for MS follow-up, obtained from conventional MRI sequences, to assist in predicting disability outcomes in people with MS.
JAMA Surg
August 2025
Department of Orthopedics, Brown University, Providence, Rhode Island.