Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: MRI is essential for diagnosing and monitoring Multiple Sclerosis. Emerging imaging biomarkers for disease progression often rely on non-conventional MRI sequences and complex post-processing tools, which are not typically available in routine clinical practice.
Aim: To provide radiologists and neurologists worldwide with simplified MRI measurements for MS follow-up, obtained from conventional MRI sequences, to assist in predicting disability outcomes in people with MS.
Methods: We conducted a scoping review covering five different online databases [PubMed, Embase, Web of Science Core collection, Cochrane library CENTRAL and Scopus] resulting in 10916 results. Relevant full-text publications were selected after abstract and full-text reviews. This review followed the PRISMA-Scr guidelines. Data extraction was carried out by the two reviewers using a standardized predefined form.
Results: Thirty-nine papers were included, identifying thirty-five manual measurements of brain and six of spinal cord. The third ventricle width (TVW) and corpus callosum area (CCA) were the most studied, with validation against their volumetric counterparts.
Conclusions: Simplified MRI measurements, such as TVW and CCA, could be easily captured, enabling radiologists to assess the neurodegenerative component of MS in real-time, without relying on non-conventional imaging techniques or post-processing tools.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.msard.2025.106670 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Abnormal Amyloid-β Duration, Tau, and Neurodegeneration in Cranial Images.
JAMA Netw Open
September 2025
School of Medicine and Public Health, University of Wisconsin-Madison, Madison.
Importance: It is unclear whether the duration of amyloid-β (Aβ) pathology is associated with neurodegeneration and whether this depends on the presence of tau.
Objective: To examine the association of longitudinal atrophy with Aβ positron emission tomography (PET)-positivity (Aβ+) and the estimated duration of Aβ+ (Aβ+ duration), controlling for tau-positivity.
Design, Setting, And Participants: Data for this longitudinal cohort study were drawn from the Wisconsin Registry for Alzheimer Prevention and the Wisconsin Alzheimer Disease Research Center Clinical Core Study.
Imaging characteristics, surgical efficacy and treatment strategies for Type IIIa atlantoaxial rotatory dislocation: a retrospective comparative study with Type III.
Eur J Orthop Surg Traumatol
September 2025
Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai, China.
Purpose: To investigate the images and treatment differences for Type IIIa atlantoaxial rotary dislocation (AARD) by comparing the imaging characteristics of patients with Type III and Type IIIa AARD.
Methods: The present study retrospectively analyzed a cohort of 35 patients who underwent posterior C1-C2 intra-articular fusion due to AARD from our hospital database. Among them, 23 patients were diagnosed with Type III AARD, while the remaining 12 patients were diagnosed with Type IIIa AARD.
Automated volumetric MRI quantification of body fat and skeletal muscle in the UK Biobank: technical validation against expert manual segmentations and comparison with single-slice techniques.
Abdom Radiol (NY)
September 2025
Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.
Objectives: The escalating global incidence of obesity, cardiometabolic disease and sarcopenia necessitates reliable body composition measurement tools. MRI-based assessment is the gold standard, with utility in both clinical and drug trial settings. This study aims to validate a new automated volumetric MRI method by comparing with manual ground truth, prior volumetric measurements, and against a new method for semi-automated single-slice area measurements.
View Article and Find Full Text PDFMissed strictures and penetrating complications on CT and MR enterography in Crohn's disease patients prior to anti-TNF therapy.
Abdom Radiol (NY)
September 2025
Department of Radiology, Mayo Clinic, Rochester, USA.
Purpose: Crohn's disease (CD) is characterized by enteric inflammation, often resulting in strictures and penetrating complications, which may alter patient management prior to the initiation of biologic therapy. Our aim is to assess the frequency of missed stricturing and internal penetrating complications in CD patients on computed tomography enterography (CTE) and magnetic resonance enterography (MRE) performed prior to anti-TNF therapy.
Methods: We retrospectively reviewed patients from two tertiary centers who underwent CTE\MRE within six months before starting anti-TNF therapy.
Bertolotti Syndrome in the Pediatric Population: A Literature Review and Management Algorithm.
J Am Acad Orthop Surg Glob Res Rev
September 2025
From the Harvard Medical School, Boston, MA (Gabriel, Hines, and Prabhat); the Lenox Hill Hospital, New York, NY (Dr. Ang); and the Boston Children's Hospital, Department of Orthopedic Surgery, Boston, MA (Dr. Liu and Dr. Hogue).
Purpose: The purpose of this study was to develop a comprehensive step-wise management algorithm for Bertolotti syndrome in the pediatric population by conducting a systematic review of the current literature regarding the diagnostic evaluation, nonsurgical and surgical treatment, and outcomes.
Methods: A systematic review of the literature was conducted using PubMed to identify studies focused on the management of Bertolotti syndrome in the pediatric population. Data extraction of clinical presentation, management strategies, imaging, and outcomes was completed.