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Objective: This study aimed to assess the impact of structural changes from repeated failed surgeries on outcomes and develop a scoring system to evaluate local palatal tissue usability in recurrent fistula repairs.
Design: A retrospective study of 51 patients with prior failed fistula surgeries using a novel scoring system for palatal tissue evaluation.
Setting: The study was conducted at a tertiary care center for craniofacial surgery.
Patients, Participants: 51 patients with recurrent palatal fistulas and at least 1prior failed surgery were included. Standardized preoperative photographs were taken.
Interventions: Patients underwent palatal fistula repair. Outcomes were assessed 12 months postoperatively, and patients were grouped by success. Two surgeons applied the scoring system to assess scar condition (evaluated by color), rugae presence, remnant flap (RF), and number of failed surgeries (NFSs).
Main Outcome Measure(s): The primary measure was the correlation between scoring system criteria and surgical outcomes, with statistical analysis determining predictive value.
Results: All criteria correlated with NFS and recurrence ( < 0.001), but only rugae, RF, and NFS showed strong associations with recurrence. Scar condition evaluated by color had lower correlations with rugae ( = 0.461), RF ( = 0.458), and NFS ( = 0.239). The final scoring system was simplified to 3 variables: rugae, RF, and NFS.
Conclusions: The revised scoring system effectively predicts success in recurrent palatal fistula repairs. Scores above 2 indicate a high risk of recurrence, suggesting alternative approaches when using local tissues.
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http://dx.doi.org/10.1177/10556656251323043 | DOI Listing |
Turk J Pediatr
September 2025
Department of Pediatric Hematology and Oncology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Background: The expression and clinical correlation of BRAFV600E mutation and programmed cell death-1 ligand 1 (PD-L1) in children with Langerhans cell histiocytosis (LCH) have been reported, but the conclusions of previous studies are inconsistent. In addition, it has been reported that elevated cathepsin S (CTSS) expression is associated with various cancers. However, there is currently no research on the correlation between CTSS and LCH.
View Article and Find Full Text PDFAppl Neuropsychol Adult
September 2025
Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México.
Negative symptoms, depression, and cognitive impairments of the schizophrenia spectrum have been associated with difficulties in daily functioning. Compensatory Cognitive Training (CCT) has shown positive effects on cognition, negative symptoms, and functioning in this population. The main objective of this pilot study was to analyze the effects of CCT on cognition and functioning in a group schizophrenia spectrum outpatients in Mexico.
View Article and Find Full Text PDFRetina
September 2025
Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, CH-3010.
Purpose: To evaluate inter-grader variability in posterior vitreous detachment (PVD) classification in patients with epiretinal membrane (ERM) and macular hole (MH) on spectral-domain optical coherence tomography (SD-OCT) and identify challenges in defining a reliable ground truth for artificial intelligence (AI)-based tools.
Methods: A total of 437 horizontal SD-OCT B-scans were retrospectively selected and independently annotated by six experienced ophthalmologists adopting four categories: 'full PVD', 'partial PVD', 'no PVD', and 'ungradable'. Inter-grader agreement was assessed using pairwise Cohen's kappa scores.
J Palliat Care
September 2025
Department of Healthcare Administration and Policy, School of Public Health, University of Nevada, Las Vegas, NV, USA.
ObjectivesRecently, atrial fibrillation (AF) has contributed to an increase in cardiovascular deaths in the U.S. Palliative care (PC) and atrial ablation (AA) procedure can elevate quality of life of high-risk AF patients, who are associated with multiple comorbidities.
View Article and Find Full Text PDFEur J Ophthalmol
September 2025
vEyes NPO, vEyes Lab, Milo, Italy.
PurposeTo introduce, describe and validate a novel, 3D-printed portable slit lamp system integrated with a macro lens-equipped smartphone, providing clinicians with a quick, easy, and effective method for obtaining high-quality clinical images.Materials and MethodsA 3D-printed portable slit lamp was developed, comprising a warm white LED light pen housed in a custom case with a biconvex lens focusing light through a 0.4 mm slit.
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