98%
921
2 minutes
20
Peritoneal surface malignancies (PSM) includes an expansive disease spectrum, ranging from low-grade appendiceal mucinous neoplasm to metastatic processes from invasive adenocarcinomas of the gastrointestinal tract. Management of PSM faces numerous challenges, from diagnosis to delivery of care, both from a treatment and navigational standpoint. This article outlines the various hurdles faced at different branch points and current management recommendations.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.soc.2024.11.002 | DOI Listing |
Case Rep Med
August 2025
Department of Gynecologic Oncology, First Affiliated Hospital, Bengbu Medical University, Bengbu 233004, Anhui, China.
Ectopic spleen (ES) is a rare complication of autologous transplant following spleen injury. Autopsy studies suggest that the true incidence rate could be as high as 67%, though only 5%-10% of patients require clinical intervention. This case report describes a highly cautionary case of ES, with an extremely long latent period.
View Article and Find Full Text PDFAnn Surg Oncol
September 2025
University Limoges, CNRS, XLIM, Limoges, France.
Int J Gynaecol Obstet
September 2025
Stanford Women's Cancer Center, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA.
In 2014, FIGO's Committee for Gynecologic Oncology revised the staging of ovarian cancer, incorporating ovarian, fallopian tube, and peritoneal cancer into the same system. Most of these malignancies are high-grade serous carcinomas (HGSCs). Stage IC is now divided into three categories: IC1 (surgical spill), IC2 (capsule ruptured before surgery or tumor on ovarian or fallopian tube surface), and IC3 (malignant cells in the ascites or peritoneal washings).
View Article and Find Full Text PDFColloids Surf B Biointerfaces
September 2025
School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China; Department of Biomaterials and Stem Cells, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Science (CAS), Suzhou 215163,
Bacterial infections and the associated inflammatory responses present significant challenges to public health, underscoring the need for innovative therapeutic strategies. In this study, novel carbon dots (QA-CDs) derived from quercetin (QU) and 4-aminophenol (4-AP) were synthesized using a one-step hydrothermal method. This approach merges the antimicrobial properties of phenolic compounds with the multifunctional advantages of carbon-based nanomaterials.
View Article and Find Full Text PDFFEBS J
September 2025
Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.
Mucosal mast cells (MMCs) are distinguished from connective tissue mast cells (MCs) by the specific cell-surface expression of integrin CD103 (also known as integrin αE/β7; αE is encoded by Itgae) and mast cell protease 1 and 2 (Mcpt1 and Mcpt2, respectively). Although the expression of the Mcpt1 and Mcpt2 genes is cooperatively regulated by the transcription factor GATA-binding protein 2 (GATA2) and transforming growth factor beta (TGF-β) signaling in MMCs, the transcriptional mechanism of the cell-surface expression of CD103 remains unknown. We herein found that surface CD103 and Itgae mRNA levels were significantly increased by the knockdown (KD) of Gata2 in mouse bone marrow-derived MCs (BMMCs), which was accelerated by TGF-β stimulation.
View Article and Find Full Text PDF