Unlocking the Potential of SC0062: A New Horizon in IgA Nephropathy Treatment?

J Am Soc Nephrol

Department of Nephrology, Chongqing Key Laboratory of Prevention and Treatment of Kidney Disease, Chongqing Clinical Research Center of Kidney and Urology Diseases, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing, China.

Published: April 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975241PMC
http://dx.doi.org/10.1681/ASN.0000000656DOI Listing

Publication Analysis

Top Keywords

unlocking potential
4
potential sc0062
4
sc0062 horizon
4
horizon iga
4
iga nephropathy
4
nephropathy treatment?
4
unlocking
1
sc0062
1
horizon
1
iga
1

Similar Publications

Electro-interactions: A review of the effects of electric fields on bacterial cells.

Biotechnol Adv

September 2025

DTU-Food, Research Group for Food Production Engineering, Laboratory of Nano-BioScience, Technical University of Denmark, Henrik Dams Allé, B202, 2800 Kongens Lyngby, Denmark. Electronic address:

Electric fields significantly influence bacterial cells by altering their physiology, membrane properties, membrane potential, and permeability, as well as their metabolism and mobility. These interactions result in observable changes in growth rates, cellular morphology, and gene expression. This review provides a comprehensive examination of the effects of electric fields on bacterial cells, focusing specifically on mechanisms such as electro-stimulation, electroporation, electrophoresis, and dielectrophoresis.

View Article and Find Full Text PDF

Unlocking low NO emissions from nitrate-laden wastewater in constructed wetlands: critical role of pyrrhotite substrate layer in mediating nitrate-dependent sulfide oxidation.

Bioresour Technol

September 2025

Research Division for Water Environmental Science and Engineering, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China. Electronic address:

Constructed wetlands (CWs) treating nitrate-rich wastewater often face incomplete denitrification and elevated NO emissions due to insufficient electron donors. Pyrrhotite as a CW substrate demonstrated potential for enhancing autotrophic denitrification through coupled sulfur and iron biological oxidation. However, the impact of pyrrhotite layer positioning on regulating NO emissions and underlying mechanisms remains unclear.

View Article and Find Full Text PDF

For meeting requirements of "green steel" and "circular economy", there was great potential and value to synthesize CO adsorbent with low price and excellent performance by using multiple solid wastes. In this study, a novel method was proposed to synthesize zeolite by blast furnace slag. CO adsorption isotherm, thermodynamic and kinetic were investigated comprehensively.

View Article and Find Full Text PDF

Achieving superior energy storage performance in dielectric materials under low electric fields remains a challenge. Most recent advancements require high fields that limit device applicability. Developing dielectric capacitors with high recoverable energy density (W), efficiency (η), and energy-storage coefficient (W/E) at low/moderate fields is critical for safer, compact, and durable electronics.

View Article and Find Full Text PDF