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Neurological disorders are a major global health concern that have a substantial impact on death rates and quality of life. accurately identifying a number of diseases Due to inherent data uncertainties and Electroencephalogram (EEG) pattern overlap, conventional EEG diagnosis methods frequently encounter difficulties. This paper proposes a novel framework that integrates FLSNN to enhance the accuracy and robustness of multiple neurological disorder disease detection from EEG signals. In multiple neurological disorders, the primary motivation is to overcome the limitations of existing methods that are unable to handle the complex and overlapping nature of EEG signals. The key aim is to provide a unified, automated solution for detecting multiple neurological disorders such as epilepsy, Parkinson's, Alzheimer's, schizophrenia, and stroke in a single framework. In the Fuzzy Logic and Spiking Neural Networks (FLSNN) framework, EEG data is preprocessed to eliminate noise and artifacts, while a fuzzy logic model is applied to handling uncertainties prior to applying spike neural networking to analyze the temporal and dynamics of the signals. Processes EEG data three times faster than traditional techniques. This framework achieves 97.46% accuracy in binary classification and 98.87% accuracy in multi-class classification, indicating increased efficiency. This research provides a significant advancement in the diagnosis of multiple neurological disorders using EEG and enhances both the quality and speed of diagnostics from the EEG signal and the advancement of AI-based medical diagnostics. at https://github.com/jainshraddha12/FLSNN , the source code will be available to the public.
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http://dx.doi.org/10.1007/s10548-025-01106-1 | DOI Listing |
Mar Biotechnol (NY)
September 2025
Yazhou Bay Innovation Institute, Hainan Tropical Ocean University, Sanya, China.
Epinephelus tukula is an economically important aquaculture animal, and a major parent in grouper crossbreeding. To better preserve and exploit E. tukula germplasm resources, a core collection (containing 34 individuals derived from 10 genetic groups) was first constructed based on phenotypic growth traits and whole-genome resequencing (WGS) data.
View Article and Find Full Text PDFFunct Integr Genomics
September 2025
The First Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, China.
Ischemic stroke (IS) has high morbidity/mortality with limited treatments. This study screened core copper homeostasis-related genes in IS and validated their function as precise intervention targets. Human IS gene chip data were retrieved from GEO, and copper homeostasis genes from multiple databases.
View Article and Find Full Text PDFBiomed Environ Sci
August 2025
Department of Epidemiology, School of Public Health, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou 215123, Jiangsu, China;Taixing Second People's Hospital, Suzhou Medical College of Soochow University, Taizhou 225400, Jiangsu, China.
Objective: Lipid oxidation is involved in the pathogenesis of atherosclerosis and may be contribute to the development of Ischemic stroke (IS). However, the lipid profiles associated with IS have been poorly studied. We conducted a pilot study to identify potential IS-related lipid molecules and pathways using lipidomic profiling.
View Article and Find Full Text PDFMult Scler
September 2025
Neuroimaging Unit, Neuroimmunology Division, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Neurology, VA Medical Center, TN Valley Healthcare System, Nashville, TN, USA.
Background: There is limited knowledge on the post-glymphatic structures such as the parasagittal dural (PSD) space and the arachnoid granulations (AGs) in multiple sclerosis (MS).
Objectives: To evaluate differences in volume and macromolecular content of PSD and AG between people with newly diagnosed MS (pwMS), clinically isolated syndrome (pwCIS), or radiologically isolated syndrome (pwRIS) and healthy controls (HCs) and their associations with clinical and radiological disease measures.
Methods: A total of 69 pwMS, pwCIS, pwRIS, and HCs underwent a 3.
Eur J Case Rep Intern Med
September 2025
Department of Internal Medicine, Hospital Universitario San Agustín, Asturias, Spain.
Background: Although splenomegaly is a common finding in Epstein-Barr virus (EBV) infection, splenic infarction is rarely reported and may be under-recognised, especially in adults. Neurological complications such as aseptic meningitis are also uncommon but documented. The simultaneous occurrence of both complications in the context of primary EBV infection is exceptional.
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