98%
921
2 minutes
20
Objectives: The objective was to aggregate the various scenarios that occur during nonconventional public health emergencies (NCPHEs) and analyze the evolutionary patterns of NCPHEs to better avoid risks and reduce social impacts. The aim was to enhance strategies for handling NCPHEs.
Study Design: News reports were crawled to obtain the scenario elements of NCPHEs and categorized into the spreading stage or derivation stage. Finally, the key scenario nodes and scenario evolution process were analyzed in combination with a corresponding emergency response assessment of each scenario by experts.
Methods: Dempster-Shafer (DS) theory and Bayesian networks (BNs) were applied for data reasoning, and a spread-derived coupled scenario-response theoretical model of NCPHEs for major public health emergencies was constructed. The scenario evolution path of COVID-19 was derived by combining seven types of major scenario states and corresponding emergency response measures extracted from 952 spreading scenarios.
Results: The 26 NCPHE spread scenarios and 41 NCPHE derivation scenarios were summarized. Optimized and pessimistic NCPHE scenario pathways were generated by combining the seven major spreading scenarios to help decision makers predict the development of NCPHEs and take timely and effective emergency response measures for key scenario nodes.
Conclusion: This study provides a new approach for understanding and managing NCPHEs, emphasizing the need to consider the specificity and complexity of such emergencies when developing decision-making strategies. Our contextual derivation model and emergency decision-making system provide practical tools with which to enhance NCPHE response capabilities and promote public health and safety.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842347 | PMC |
http://dx.doi.org/10.3389/fpubh.2025.1489904 | DOI Listing |
J Med Internet Res
September 2025
Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
Background: The loss of a loved one is a common yet stressful event in later life. Internet- and mobile-based interventions have been proposed as an effective treatment approach for individuals with prolonged grief.
Objective: The AgE-health study aimed to investigate the efficacy of an eHealth intervention, trauer@ktiv, in reducing prolonged grief symptoms in a sample of older adults.
Proc Natl Acad Sci U S A
September 2025
State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug De
Proliferative retinopathy is a leading cause of irreversible blindness in humans; however, the molecular mechanisms behind the immune cell-mediated retinal angiogenesis remain poorly elucidated. Here, using single-cell RNA sequencing in an oxygen-induced retinopathy (OIR) model, we identified an enrichment of sorting nexin (SNX)-related pathways, with SNX3, a member of the SNX family that is involved in endosomal sorting and trafficking, being significantly upregulated in the myeloid cell subpopulations of OIR retinas. Immunostaining showed that SNX3 expression is markedly increased in the retinal microglia/macrophages of mice with OIR, which is mainly located within and around the neovascular tufts.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Department of Biology, Stanford University, Stanford, CA 94305.
Climate change is expected to pose significant threats to public health, particularly vector-borne diseases. Despite dramatic recent increases in dengue that many anecdotally connect with climate change, the effect of anthropogenic climate change on dengue remains poorly quantified. To assess this link, we assembled local-level data on dengue across 21 countries in Asia and the Americas.
View Article and Find Full Text PDFSoc Work Public Health
September 2025
Department of Healthcare Management, Çankırı Karatekin University, Çankırı, Türkiye.
This study investigates socioeconomic disparities in chronic respiratory diseases and the factors contributing to these inequalities, using data from the 2019 Turkish Health Survey. Multivariate logistic regression and Oaxaca-Blinder decomposition analyses reveal that 13.10% of adults aged 25 and older in Turkey suffer from chronic respiratory diseases, with a significantly higher prevalence among lower socioeconomic status (SES) individuals.
View Article and Find Full Text PDFHealth Educ Res
August 2025
Department of Social Sciences and Health Policy, Medical Center Boulevard, Wake Forest University School of Medicine, Winston-Salem, NC 27157, United States.
Minoritized racial, ethnic, sexual, and gender communities and populations face profound health disparities and their engagement in research remains low. In a randomized controlled trial, our community-based participatory research partnership tested the efficacy of ChiCAS, an HIV prevention intervention designed to increase pre-exposure prophylaxis use among Spanish-speaking transgender Latinas. Of 161 eligible Spanish-speaking transgender Latinas screened, we enrolled 144, achieving an 89% participation rate, and retained 94% at 6-month follow-up.
View Article and Find Full Text PDF