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Digital implementations of discrete Fourier transforms (DFT) are a mainstay in feature assessment of recorded biopotentials, particularly in the quantification of biomarkers of neurological disease state for adaptive deep brain stimulation. Fast Fourier transform (FFT) algorithms and architectures present a substantial power demand from onboard batteries in implantable medical devices, necessitating the development of ultra-low power Fourier transform methods in resource-constrained environments. Numerous FFT architectures aim to optimize power and resource demand through computational efficiency; however, prioritizing the reduction of logic complexity at the cost of additional computations can be equally or more effective. This paper introduces a minimal-architecture single-delay feedback discrete Fourier transform (mSDF-DFT) for use in ultra-low-power field programmable gate array applications and shows energy and power improvements over state-of-the-art low-power DFT and FFT methods. In a neural sensing application, we observe a 33% reduction in dynamic power and 4% reduction in resource utilization when compared to state-of-the-art FFT algorithms; 38% reduction in dynamic power and 4% reduction in resource utilization when compared to Goertzel Algorithm. While designed for use in closed-loop deep brain stimulation and medical device implementations, the mSDF-DFT is also easily extendable to any ultra-low-power embedded application.
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http://dx.doi.org/10.1101/2025.02.13.637868 | DOI Listing |
Front Neurol
August 2025
Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Introduction: External continuous perturbations using a motion platform have been developed by employing either sum-of-sines (SoS) or a pseudorandom ternary sequence (PRTS) of numbers to quantify body sway evoked in the medial-lateral (ML) or anterior-posterior (AP) directions, which ultimately helps understand the human postural control system. These stimuli have been provided via pitch tilts of the motion platform for evaluations of AP balance responses or roll tilts for ML balance responses. However, little is known about whether a healthy postural control system responds to 2-dimensional (2D) perturbations similarly when the perturbation stimuli are provided in semicircular canal coordinates (i.
View Article and Find Full Text PDFFront Neuroinform
August 2025
Department of Computer Science and Engineering, Nirma University, Ahmedabad, Gujarat, India.
Electroencephalogram (EEG) signal analysis plays a vital role in diagnosing and monitoring alcoholism, where accurate classification of individuals into alcoholic and control groups is essential. However, the inherent noise and complexity of EEG signals pose significant challenges. This study investigates the impact of three signal denoising techniques' Discrete Wavelet Transform(DWT), Discrete Fourier Transform(DFT), and Discrete Cosine Transform (DCT) Non EEG signal classification performance.
View Article and Find Full Text PDFCytotechnology
October 2025
Core Facilities, Zhejiang University School of Medicine, Hangzhou, 310058 China.
Super-resolution fluorescence microscopy (SRM) has enabled visualization of nanoscale cellular structures, but systematic evaluation of resolution assessment methods across diverse biological structures and SRM modalities remains lacking. Here, we comparatively assessed three resolution metrics-Full Width at Half Maximum (FWHM), decorrelation analysis, and Fourier Ring Correlation (FRC)-across two SRM techniques (Super-resolution Radial Fluctuation, SRRF; Stimulated Emission Depletion, STED) using key subcellular structures: microtubules (filaments), mitochondria (membranes), and nuclear pore protein Nup98 (single particles) in HeLa/U2OS cells. Our results showed decorrelation analysis provided robust resolution estimates across all structures and modalities (confocal/SRRF/STED), exhibiting superior performance for dense nuclear pore complexes where FWHM failed due to overlapping point spread functions.
View Article and Find Full Text PDFSensors (Basel)
August 2025
Master in ICT for Education, Smart Grid Research Group (GIREI), Universidad Politécnica Salesiana, Quito EC170525, Ecuador.
This paper explores the application of transform-domain sparsification and compressed sensing (CS) techniques to improve the efficiency and quality of magnetic resonance imaging (MRI). We implement and evaluate three sparsifying methods-discrete wavelet transform (DWT), fast Fourier transform (FFT), and discrete cosine transform (DCT)-which are used to simulate subsampled reconstruction via inverse transforms. Additionally, one accurate CS reconstruction algorithm, basis pursuit (BP), using the L-MAGIC toolbox, is implemented as a benchmark based on convex optimization with L-norm minimization.
View Article and Find Full Text PDFIEEE Trans Signal Inf Process Netw
May 2025
Halıcıoğlu Data Science Institute and the Neurosciences Graduate Program, UC San Diego, CA 92093 USA.
Graph signal processing (GSP) is a prominent framework for analyzing signals on non-Euclidean domains. The graph Fourier transform (GFT) uses the combinatorial graph Laplacian matrix to reveal the spectral decomposition of signals in the graph frequency domain. However, a common challenge in applying GSP methods is that in many scenarios the underlying graph of a system is unknown.
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