98%
921
2 minutes
20
Introduction: Road traffic crashes globally cause 1.3 million deaths yearly and the rate of nonfatal crashes is increasing. Nonfatal injuries impact long-term quality of life, which is often overlooked in evaluations. The preferred method for using health-related quality of life and disability for evaluating road safety interventions have not been established.
Method: A scoping review of peer-reviewed and grey literature was undertaken to understand health-related quality of life and disability measures currently used to evaluate road safety interventions. We included English language studies that used any health-related quality of life or disability measure to evaluate any real-world intervention aimed at reducing the number or severity of road traffic crashes.
Results: Nine different health-related quality of life measures were used in the 18 included studies. The most commonly used measure was a quality-adjusted life year, which was used by seven studies, followed by the Glasgow Outcome Scale used by five studies. Two studies used two different health-related quality of life or disability measures. Five studies used primary data (collected directly for the purpose of the study) and 13 studies used existing data sources not explicitly collected for the reported evaluation. Of these 13 studies, 5 used an injury registry as the data source. Six different methods of deriving utility weights for calculating quality-adjusted life years were used.
Conclusions: This review found that evaluations of road safety interventions using health-related quality of life or disability measures were rare. There was a lack of consistency in the measures used which prevented comparisons across evaluations. Further, inconsistent methods were used to derive utility weights for quality-adjusted life years.
Practical Applications: Future evaluations of roads safety interventions need to consider longer-term outcomes. Consistent methods for measuring health-related quality of life and disability burden are needed, as are empirically derived utility weights for quality-adjusted life years.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jsr.2024.11.028 | DOI Listing |
Scand J Med Sci Sports
September 2025
Department of Dermatology and Allergy Biederstein, School of Medicine and Health, TUM University Hospital Rechts der Isar, Munich, Germany.
In wheat allergy dependent on augmentation factors (WALDA), allergic reactions occur when wheat ingestion is combined with exercise or rarely other augmentation factors. We analyzed clinical characteristics and disease burden in recreationally active and trained individuals with WALDA diagnosed by oral challenge test. Clinical characteristics, serological data, and quality of life (QOL) questionnaires were analyzed and completed with follow-up interviews.
View Article and Find Full Text PDFInt J Gynaecol Obstet
September 2025
Department of Gynecology and Obstetrics, Justus Liebig University Giessen, Giessen, Germany.
Even though uterine fibroids are a widespread condition, the range of approved medical treatment options remains limited. In fact, only a few drugs are officially approved for the therapy of fibroids. In both the USA and the European Medicines Agency region, selected gonadotropin-releasing hormone (GnRH) antagonists have been approved for this indication.
View Article and Find Full Text PDFJ Investig Allergol Clin Immunol
September 2025
Department of Ophthalmology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Background And Objectives: Pollen-food allergy syndrome (PFAS) is a frequent comorbidity in individuals with hay fever. Identifying risk factors and allergen clusters can aid targeted interventions and management strategies. Objective: This study characterizes PFAS in patients with hay fever and identifies associated risk factors using the mobile health platform, AllerSearch.
View Article and Find Full Text PDFJ Sci Food Agric
September 2025
Microbial Biotechnology Research Group, School of Life Sciences and Technology, Institut Teknologi Bandung, Bandung, Indonesia.
Background: Secondary fermentation can reduce variability in cocoa bean quality caused by the spontaneous, uncontrolled nature of primary fermentation. However, its optimization remains unexplored. This study evaluated the improvement of secondary fermentation through the combined use of Citrus limon peel and inoculation with Candida tropicalis H1Y4-1 as a starter.
View Article and Find Full Text PDFStroke
September 2025
Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China (H.Z., K.H., Q.G.).
Background: Poststroke cognitive impairment (PSCI) affects 30% to 50% of stroke survivors, severely impacting functional outcomes and quality of life. This study uses functional near-infrared spectroscopy (fNIRS) to assess task-evoked brain activation and its potential for stratifying the severity in patients with PSCI.
Method: A cross-sectional study was conducted at Nanchong Central Hospital between June 2023 and April 2024.