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Transmetatarsal amputation versus multiple toes amputations for non-ischemic diabetic foot infection management.
Surgeon
September 2025
Department of Vascular and Endovascular Surgery, Waterford University Hospital, Waterford, Ireland; University College Cork, Ireland; Department of Vascular and Endovascular Surgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address:
Background: The management of diabetic foot infections (DFIs) is a complex multidisciplinary process and often necessitates surgical interventions. Unfortunately, amputations such as single or multiple toes amputations (MTA) or full transmetatarsal amputation (TMA) are often the unavoidable solution. This study aimed to compare the clinical outcomes of TMA versus MTA in managing non-ischemic diabetic foot infections.
View Article and Find Full Text PDFComplications in Distal Minimally Invasive Metatarsal Osteotomies: Systematic Review and Meta-Analysis.
Medicina (Kaunas)
August 2025
Podiatry Department, Faculty of Medicine and Health Sciences, Valencia Catholic University San Vicente Mártir, 46001 Valencia, Spain.
: Minimally invasive distal metatarsal osteotomy (DMMO) has established itself as an effective surgical technique for the treatment of metatarsalgia, notable for its reduced postoperative pain and faster recovery. However, doubts remain regarding the frequency and nature of postoperative complications. The objective of this systematic review and meta-analysis was to evaluate the incidence of the most frequent complications associated with the DMMO technique, including prolonged edema, delayed bone healing, transfer metatarsalgia, floating toe, and persistent pain.
View Article and Find Full Text PDFSkin perfusion pressure, distal blood pressure vs. trans cutaneous oxygen pressure for predicting wound healing after major amputation.
Clin Physiol Funct Imaging
September 2025
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Objective: To compare measurements of skin perfusion pressure (SPP) and transcutaneous oxygen pressure (TcPO) to predict postamputation wound healing according to amputation level.
Methods: This study was conducted as a prospective two-centre, head-to-head study.
Results: Fifty-two patients had SPP, TcPO measured (below and above the knee), and toe and ankle blood pressure measurements taken before major amputation.
Enhancing diabetic foot wound healing with topical macrophage-regulating cream (ON101): a case series.
J Wound Care
August 2025
Division of Plastic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Objective: A number of treatments have been developed to treat hard-to-heal (chronic) diabetic foot ulcers (DFUs). This case series the use of ON101-a new topical macrophage regulatory cream for the treatment of DFUs, that helped achieve limb-salvage outcomes with an adequate safety profile.
Method: Patients with hard-to-heal DFUs-primarily on the toes and plantar surfaces-were enrolled in the study.
Effectiveness of periwound regional oxygen saturation as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia.
J Wound Care
August 2025
Department of Plastic and Reconstructive Surgery, Kyorin University Hospital, Tokyo, Japan.
Objective: To verify the utility and accuracy of periwound regional oxygen saturation (rSO) as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia (CLTI), and compare the results with skin perfusion pressure (SPP) measurements.
Method: Patients with hard-to-heal (chronic) toe wounds and CLTI, and who had undergone toe rSO (near wound), forefoot rSO and SPP measurements, were retrospectively selected. Following the measurements, the patients were treated conservatively, and the progress of wound healing was evaluated 28-91 days after the rSO/SPP measurements.