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http://dx.doi.org/10.1210/clinem/dgaf012 | DOI Listing |
Anal Chem
September 2025
College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P. R. China.
High-fat foods are decomposed into fatty acids during digestion and absorption, primarily occurring in the gastrointestinal tract, and numerous studies have indicated that long-term high-fat diets significantly increase the incidence of intestinal disorders. As a critical intestinal hormone, serotonin (5-hydroxytryptamine, 5-HT) is involved in regulating intestinal peristalsis, secretion, and visceral sensitivity. However, due to the lack of methods capable of reproducing intestinal mechanical activities and in situ monitoring of 5-HT levels, the influence of high-fat diets on intestinal 5-HT release remains unclear.
View Article and Find Full Text PDFInt J Vitam Nutr Res
July 2025
Department of Urology and Andrology, The First Affiliated Hospital, Sun Yat-sen University, 510080 Guangzhou, Guangdong, China.
Background: Obesity, a prevalent global health issue, is associated with testosterone deficiency (TD). A body shape index (ABSI) provides a more precise assessment of obesity and visceral fat, but its relationship with testosterone remains unclear. This study aimed to explore the association between ABSI and testosterone levels leading to TD.
View Article and Find Full Text PDFFood Funct
September 2025
School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
: The therapeutic potential of vegetarian diets in metabolic dysfunction-associated steatotic liver disease (MASLD) remains understudied in Asian populations. This randomized controlled trial aimed to evaluate the effects of a culturally adapted 6-month lacto-ovo-vegetarian diet (LOV-D) on hepatic steatosis and cardiometabolic risk factors through weight loss. : In this randomized trial, 220 Chinese adults with MASLD were assigned to LOV-D ( = 110) or an omnivore diet ( = 110) for 6 months.
View Article and Find Full Text PDFJ Obes Metab Syndr
September 2025
Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: This study explores how relative skeletal muscle mass is associated with the development of metabolic dysfunction-associated steatotic liver disease (MASLD) and the remission of baseline MASLD in a community-based population cohort.
Methods: The study included 1,544 participants with an average age of 58 years. All participants underwent baseline and follow-up assessments in 2015 or 2016.
Geriatr Gerontol Int
September 2025
Department of Internal Medicine, Chung-Ang University Hospital, Seoul, South Korea.
Aim: Patients undergoing maintenance hemodialysis (MHD) often have multiple comorbidities and are vulnerable to minor stressors that frequently result in hospitalization. Recent advances have enabled the easy estimation of body composition in clinical settings. This study retrospectively investigated changes in body composition associated with hospitalization in patients receiving MHD.
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